153038

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1794161..1794686 Replicon chromosome
Accession NZ_CP050541
Organism Levilactobacillus brevis strain NSMJ23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HCC75_RS09095 Protein ID WP_043023228.1
Coordinates 1794161..1794424 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HCC75_RS09100 Protein ID WP_043023227.1
Coordinates 1794417..1794686 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCC75_RS09085 1791010..1792062 - 1053 WP_087609247.1 alpha/beta hydrolase fold domain-containing protein -
HCC75_RS09090 1792124..1793503 - 1380 WP_193134334.1 MFS transporter -
HCC75_RS09095 1794161..1794424 - 264 WP_043023228.1 Txe/YoeB family addiction module toxin Toxin
HCC75_RS09100 1794417..1794686 - 270 WP_043023227.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HCC75_RS09105 1795215..1796858 + 1644 WP_141268087.1 peptide ABC transporter substrate-binding protein -
HCC75_RS09110 1797048..1797578 - 531 WP_087609241.1 hypothetical protein -
HCC75_RS09115 1797565..1798053 - 489 WP_087609240.1 hypothetical protein -
HCC75_RS09120 1798288..1799286 - 999 WP_011668750.1 LacI family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10259.70 Da        Isoelectric Point: 9.8184

>T153038 WP_043023228.1 NZ_CP050541:c1794424-1794161 [Levilactobacillus brevis]
MNKLFTENAWQDYLWLLKNDRRALKRVNLLLQDISRTPFSGIGKPESLHGDFTGYWSRRVNEKDRLVYAADEKTITILAC
RTHYGDK

Download         Length: 264 bp

>T153038 NZ_CP066748:3028070-3028177 [Escherichia coli O157:H7]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10329.45 Da        Isoelectric Point: 4.8500

>AT153038 WP_043023227.1 NZ_CP050541:c1794686-1794417 [Levilactobacillus brevis]
MEATTYTDFRKNLKKYMDKATGDFEPITITRKDHQNAVLISEEEYNNMLENRYILDNPTNREWLQASLKQAKDGQVAAHH
LVTPSADDE

Download         Length: 270 bp

>AT153038 NZ_CP066748:c3028022-3027963 [Escherichia coli O157:H7]
GTCTGGTTTCAAGATTAGCCCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References