Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 455097..455738 Replicon chromosome
Accession NZ_CP050523
Organism Acinetobacter baumannii strain VB7036

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HBM81_RS02225 Protein ID WP_000607077.1
Coordinates 455349..455738 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HBM81_RS02220 Protein ID WP_011860336.1
Coordinates 455097..455342 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBM81_RS02200 450601..451608 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
HBM81_RS02205 451627..452004 + 378 WP_001216380.1 50S ribosomal protein L17 -
HBM81_RS02210 452186..453676 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
HBM81_RS02215 453725..454897 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
HBM81_RS02220 455097..455342 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
HBM81_RS02225 455349..455738 + 390 WP_000607077.1 membrane protein Toxin
HBM81_RS02230 456508..457593 + 1086 WP_000049106.1 hypothetical protein -
HBM81_RS02235 457671..458237 + 567 WP_000651538.1 rhombosortase -
HBM81_RS02240 458425..460620 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T153014 WP_000607077.1 NZ_CP050523:455349-455738 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T153014 NZ_CP066721:1993351-1993815 [Staphylococcus xylosus]
ATGAGAAATTATGAAAATTTATTAGCAGAGTATGATGACGAAATCATCATTGAGGAAACCAATTTAAAGAGAGGTCTTGC
TGGTTTATATTTAGGCGAAATCATCCTTATTGAAAAACGCATGAATTCTGTAAATAAACTCGAAACTTTATATGAAGAAA
TCGGACACCATTTAGTTACATATGGAGATATTCGAGATCAATCTAAAATGTTAAATCGAAAATTTGAATTAAAAGCAAGA
CGTTTAGGCTCTGAATTAGCTATTTCGCTTGATGGAATTATAGATGCTTTCTACCACGGAGTACATAACTTGTTTGAGAT
GTCAGAATATTTCAACGTTTCAGAGGAATATGTATTAAATACATTGAAACATTACAAAATGAAATACGGTTTAGATGTAT
ATTACAAGGGTTATGTAATTAAATTCGAACCTTTACAAGTGTTTGAACATTATAACTGGGAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT153014 WP_011860336.1 NZ_CP050523:455097-455342 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT153014 NZ_CP066721:1993007-1993339 [Staphylococcus xylosus]
ATGTTTAGCCAAAACTTAAAATACTTAAGAAATAAGCATAATATGGAACAAATCGATCTTGCACACAAACTTGGAAGAAA
GAGCGCATCTAGTATAAGTGAATGGGAAAAAGGCAAATACACTCCTAAAATGAAGACATTATTAGAAATAGCGTCAATAT
TTAATGTTAATATAGATGATTTAATGGGAGATGATTTGGCAACACCAAAAAAAGAAAATCCAAAATCATCTTTTGAAACC
ATCGCTGCTCATTTAGATGGTGATTTAACAGAAGAAGAATGGCAAGAGATATTGGATTATGCAGAATTCGTTAAAAGCAA
GCGTAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References