Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4301430..4302114 Replicon chromosome
Accession NZ_CP050520
Organism Enterobacter sp. DNB-S2

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag HB664_RS20755 Protein ID WP_219940854.1
Coordinates 4301791..4302114 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HB664_RS20750 Protein ID WP_101862777.1
Coordinates 4301430..4301753 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB664_RS20715 (HB664_20735) 4296987..4297427 + 441 WP_063410040.1 hypothetical protein -
HB664_RS20720 (HB664_20740) 4297463..4297825 + 363 WP_219940145.1 hypothetical protein -
HB664_RS20725 (HB664_20745) 4298221..4298565 + 345 WP_219940146.1 hypothetical protein -
HB664_RS20730 (HB664_20750) 4298562..4299623 + 1062 WP_219940147.1 hypothetical protein -
HB664_RS20735 (HB664_20755) 4299854..4300672 + 819 WP_219940148.1 DUF932 domain-containing protein -
HB664_RS20740 (HB664_20760) 4300705..4301178 + 474 WP_130942920.1 DNA repair protein RadC -
HB664_RS20745 (HB664_20765) 4301187..4301408 + 222 WP_219940149.1 DUF987 family protein -
HB664_RS20750 (HB664_20770) 4301430..4301753 + 324 WP_101862777.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HB664_RS20755 (HB664_20775) 4301791..4302114 + 324 WP_219940854.1 TA system toxin CbtA family protein Toxin
HB664_RS20760 (HB664_20780) 4302726..4303082 + 357 WP_029740047.1 hypothetical protein -
HB664_RS20765 (HB664_20785) 4303257..4303814 + 558 WP_033146331.1 YceI family protein -
HB664_RS20770 (HB664_20790) 4303806..4304597 - 792 WP_219940150.1 hypothetical protein -
HB664_RS20775 (HB664_20795) 4304594..4305124 - 531 WP_081318797.1 RNA polymerase sigma factor -
HB664_RS20780 (HB664_20800) 4305132..4305659 - 528 WP_033146334.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12138.75 Da        Isoelectric Point: 4.7869

>T153010 WP_219940854.1 NZ_CP050520:4301791-4302114 [Enterobacter sp. DNB-S2]
ISSVPATVPVSSRLSPVQVWQQLLTYLLEQHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELVRIDRKGFSW
QEQTPYISVVDILRARRSTGLLKTNVE

Download         Length: 324 bp

>T153010 NZ_CP066721:956380-956580 [Staphylococcus xylosus]
GTGCAATCAAAAATAATTTACGTCTCAGGTATTAATTCAGAACGACAATATCAAATAAAACAACGATTAATGAATGTTAT
AGGTGTACACAATGTTGCTATAGATAGTGATAAAGGAGAAATACTTGTCGATTTTGAAACACCTGCGAGTTTAAATAATT
TAGAAAAAGAAATTTATGATCTTGGATATCAAATATTTTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11983.69 Da        Isoelectric Point: 7.0268

>AT153010 WP_101862777.1 NZ_CP050520:4301430-4301753 [Enterobacter sp. DNB-S2]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNKDETLRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLHHN
GLTCEADTLGSHGYVYIVIYPQASATQ

Download         Length: 324 bp

>AT153010 NZ_CP066721:956072-956365 [Staphylococcus xylosus]
GTGACAGAAATACAAAAAGCACATCATTCAGACCAAATAAAATCAAATTTGAAATCAAGACTAAATAGAATAGAAGGGCA
AGTGCGAGCAATAAACCGTATGGTAGATGAAGATGTTTATTGTGACGATGTACTTACTCAAATTAGAGCGACACGTTCTG
CACTAAATAGCGTAGCAACTAAATTGTTGGATCATCATATGAAAAGTTGCATCATGGATAAAGTGGAAAAAGGTCAACAA
GAAGAAGCAATGGAAGAGTTATTAGTAACTTTTCAAAAATTAATGAAGGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References