Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3451099..3451244 Replicon chromosome
Accession NZ_CP050520
Organism Enterobacter sp. DNB-S2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3451106..3451209 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3451099..3451244 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB664_RS16510 (HB664_16515) 3446449..3446601 + 153 WP_006809793.1 DUF1317 family protein -
HB664_RS16515 (HB664_16520) 3446598..3447080 + 483 WP_219939844.1 class I SAM-dependent methyltransferase -
HB664_RS16520 (HB664_16525) 3447077..3447736 + 660 WP_219939845.1 MT-A70 family methyltransferase -
HB664_RS16525 (HB664_16530) 3447733..3447951 + 219 WP_219939846.1 hypothetical protein -
HB664_RS16530 (HB664_16535) 3447948..3448256 + 309 WP_219939847.1 hypothetical protein -
HB664_RS16535 (HB664_16540) 3448351..3448569 + 219 WP_219939848.1 TraR/DksA family transcriptional regulator -
HB664_RS16540 (HB664_16545) 3448571..3449059 - 489 WP_219939849.1 hypothetical protein -
HB664_RS16545 (HB664_16550) 3449273..3449536 + 264 Protein_3229 DUF550 domain-containing protein -
HB664_RS16550 (HB664_16555) 3449702..3449974 + 273 WP_219939851.1 excisionase -
HB664_RS16555 (HB664_16560) 3449943..3451028 + 1086 WP_219939852.1 phage integrase Arm DNA-binding domain-containing protein -
- 3451099..3451244 + 146 - - Antitoxin
- 3451106..3451209 - 104 - - Toxin
HB664_RS16560 (HB664_16565) 3451348..3451686 - 339 WP_033145840.1 YebY family protein -
HB664_RS16565 (HB664_16570) 3451703..3452572 - 870 WP_033145841.1 copper homeostasis membrane protein CopD -
HB664_RS16570 (HB664_16575) 3452574..3452945 - 372 WP_033145842.1 CopC domain-containing protein YobA -
HB664_RS16575 (HB664_16580) 3453082..3453312 + 231 WP_008500465.1 DNA polymerase III subunit theta -
HB664_RS16580 (HB664_16585) 3453423..3454073 + 651 WP_033145843.1 carbon-nitrogen hydrolase family protein -
HB664_RS16585 (HB664_16590) 3454098..3454760 + 663 WP_010432611.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3383769..3457550 73781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T153000 NZ_CP050520:c3451209-3451106 [Enterobacter sp. DNB-S2]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153000 NZ_CP050520:3451099-3451244 [Enterobacter sp. DNB-S2]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References