Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 208888..209159 Replicon chromosome
Accession NZ_CP050498
Organism Escherichia coli strain RM13322

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 209018..209121 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 208888..209159 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCR07_RS01250 205443..206105 - 663 WP_000944256.1 exodeoxyribonuclease X -
HCR07_RS01255 206129..206785 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HCR07_RS01260 206887..207117 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HCR07_RS01265 207256..207630 + 375 WP_000204700.1 CopC domain-containing protein YobA -
HCR07_RS01270 207634..208506 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HCR07_RS01275 208519..208860 + 342 WP_000976472.1 YebY family protein -
- 208888..209159 - 272 - - Antitoxin
- 209018..209121 + 104 - - Toxin
HCR07_RS01280 209256..209912 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
HCR07_RS01285 209913..210104 - 192 WP_001296140.1 YebW family protein -
HCR07_RS01290 210209..210445 - 237 WP_001295499.1 DUF1480 family protein -
HCR07_RS01295 210563..212002 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T152929 NZ_CP050498:209018-209121 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT152929 NZ_CP050498:c209159-208888 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACATATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References