Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 7070961..7071570 Replicon chromosome
Accession NZ_CP050440
Organism Tolypothrix sp. PCC 7910

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HCG51_RS28250 Protein ID WP_167726220.1
Coordinates 7070961..7071323 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HCG51_RS28255 Protein ID WP_167727710.1
Coordinates 7071313..7071570 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCG51_RS28230 7065996..7066307 + 312 WP_096576410.1 P-II family nitrogen regulator -
HCG51_RS28235 7066304..7067005 + 702 WP_167726217.1 carbonic anhydrase -
HCG51_RS28240 7067088..7067729 + 642 WP_167726218.1 Uma2 family endonuclease -
HCG51_RS28245 7067838..7070630 - 2793 WP_167726219.1 preprotein translocase subunit SecA -
HCG51_RS28250 7070961..7071323 - 363 WP_167726220.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HCG51_RS28255 7071313..7071570 - 258 WP_167727710.1 hypothetical protein Antitoxin
HCG51_RS28260 7071751..7072305 - 555 WP_167726221.1 cytochrome C -
HCG51_RS28265 7072447..7076013 + 3567 WP_167726222.1 CHAT domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13875.59 Da        Isoelectric Point: 4.9534

>T152875 WP_167726220.1 NZ_CP050440:c7071323-7070961 [Tolypothrix sp. PCC 7910]
MQSDNRVSIRFADEFEEKLYRLSKRFRNIRSDVQPIIEQLQQGNIVGDRISGLGEEYIVYKVRVRNSNIQKGKSAGYRLI
YQLESPTSILLLTIYSKSDQEDIAANEIRNILADFDTEDG

Download         Length: 363 bp

>T152875 NZ_CP066553:188909-189319 [Enterobacter hormaechei subsp. xiangfangensis]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGTCTGGTCGCGGC
AATGGTGTTATTGGTGCCGTGGCCGCTAAGCTATACCCCTCTGTGGCTGCTTTTGCTGTCGTTTGTGGTGTTTGATAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAAATGATAGGGACGCCGTGGATGCTCAACACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGGGATCTGCGCCGGCTAATCGTGCAACAGCCAA
CGCAGGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9513.80 Da        Isoelectric Point: 4.4169

>AT152875 WP_167727710.1 NZ_CP050440:c7071570-7071313 [Tolypothrix sp. PCC 7910]
MKAIEVTGKIDAQGNLILDEPIHGTTYPHQVRVIVLVPEPAESEELDPDDTPVEEIKASLRRALKQAKMGQTRPISELWD
RIDAE

Download         Length: 258 bp

>AT152875 NZ_CP066553:188662-188928 [Enterobacter hormaechei subsp. xiangfangensis]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References