Detailed information of TA system TA152875

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 7070961..7071570
• Replicon: chromosome
• Accession: NZ_CP050440
• Organism: Tolypothrix sp. PCC 7910

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HCG51_RS28250
• Protein ID: WP_167726220.1
• Coordinates: 7070961..7071323 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HCG51_RS28255
• Protein ID: WP_167727710.1
• Coordinates: 7071313..7071570 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCG51_RS28230	7065996..7066307	+	312	WP_096576410.1	P-II family nitrogen regulator	-
HCG51_RS28235	7066304..7067005	+	702	WP_167726217.1	carbonic anhydrase	-
HCG51_RS28240	7067088..7067729	+	642	WP_167726218.1	Uma2 family endonuclease	-
HCG51_RS28245	7067838..7070630	-	2793	WP_167726219.1	preprotein translocase subunit SecA	-
HCG51_RS28250	7070961..7071323	-	363	WP_167726220.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HCG51_RS28255	7071313..7071570	-	258	WP_167727710.1	hypothetical protein	Antitoxin
HCG51_RS28260	7071751..7072305	-	555	WP_167726221.1	cytochrome C	-
HCG51_RS28265	7072447..7076013	+	3567	WP_167726222.1	CHAT domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (3-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13875.59 Da
• Isoelectric Point: 4.9534

>T152875 WP_167726220.1 NZ_CP050440:c7071323-7070961 [Tolypothrix sp. PCC 7910]
MQSDNRVSIRFADEFEEKLYRLSKRFRNIRSDVQPIIEQLQQGNIVGDRISGLGEEYIVYKVRVRNSNIQKGKSAGYRLI
YQLESPTSILLLTIYSKSDQEDIAANEIRNILADFDTEDG

Nucleotide

• Length: 363 bp

>T152875 NZ_CP066553:188909-189319 [Enterobacter hormaechei subsp. xiangfangensis]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGTCTGGTCGCGGC
AATGGTGTTATTGGTGCCGTGGCCGCTAAGCTATACCCCTCTGTGGCTGCTTTTGCTGTCGTTTGTGGTGTTTGATAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAAATGATAGGGACGCCGTGGATGCTCAACACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGGGATCTGCGCCGGCTAATCGTGCAACAGCCAA
CGCAGGAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9513.80 Da
• Isoelectric Point: 4.4169

>AT152875 WP_167727710.1 NZ_CP050440:c7071570-7071313 [Tolypothrix sp. PCC 7910]
MKAIEVTGKIDAQGNLILDEPIHGTTYPHQVRVIVLVPEPAESEELDPDDTPVEEIKASLRRALKQAKMGQTRPISELWD
RIDAE

Nucleotide

• Length: 258 bp

>AT152875 NZ_CP066553:188662-188928 [Enterobacter hormaechei subsp. xiangfangensis]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA