Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 450390..451031 Replicon chromosome
Accession NZ_CP050421
Organism Acinetobacter baumannii strain VB2200

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HBN41_RS02185 Protein ID WP_000607077.1
Coordinates 450642..451031 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HBN41_RS02180 Protein ID WP_011860336.1
Coordinates 450390..450635 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBN41_RS02160 445894..446901 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
HBN41_RS02165 446920..447297 + 378 WP_001216380.1 50S ribosomal protein L17 -
HBN41_RS02170 447479..448969 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
HBN41_RS02175 449018..450190 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
HBN41_RS02180 450390..450635 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
HBN41_RS02185 450642..451031 + 390 WP_000607077.1 membrane protein Toxin
HBN41_RS02190 451801..452886 + 1086 WP_000049106.1 hypothetical protein -
HBN41_RS02195 452964..453530 + 567 WP_000651538.1 rhombosortase -
HBN41_RS02200 453718..455913 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T152856 WP_000607077.1 NZ_CP050421:450642-451031 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T152856 NZ_CP066546:c3235662-3235369 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCGTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT152856 WP_011860336.1 NZ_CP050421:450390-450635 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT152856 NZ_CP066546:c3235367-3235077 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGTCCGACACACTGGTTCCCTTCGACATCTCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGACGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCACTGGGCCTGCAGCTGTGCACCACCGTGCCCCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References