Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3263066..3263707 Replicon chromosome
Accession NZ_CP050400
Organism Acinetobacter baumannii strain VB11737

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HBM80_RS16135 Protein ID WP_000607077.1
Coordinates 3263066..3263455 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HBM80_RS16140 Protein ID WP_011860336.1
Coordinates 3263462..3263707 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBM80_RS16120 3258184..3260379 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
HBM80_RS16125 3260567..3261133 - 567 WP_000651538.1 rhombosortase -
HBM80_RS16130 3261211..3262296 - 1086 WP_000049106.1 hypothetical protein -
HBM80_RS16135 3263066..3263455 - 390 WP_000607077.1 membrane protein Toxin
HBM80_RS16140 3263462..3263707 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
HBM80_RS16145 3263907..3265079 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
HBM80_RS16150 3265128..3266618 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
HBM80_RS16155 3266800..3267177 - 378 WP_001216380.1 50S ribosomal protein L17 -
HBM80_RS16160 3267196..3268203 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T152832 WP_000607077.1 NZ_CP050400:c3263455-3263066 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T152832 NZ_CP066537:c9649-9335 [Klebsiella pneumoniae]
ATGCCACAGGTAACGATTTCCGCGCTGGCACAGCGCGATTTACAACGCCTTCAGGACTTTCTCAAAACCAAAAATCGGCT
GGCAGCCAGAAAAGGAGGTGAGGTGATCGTCCGGGCTATCCAGCAACTGAAAACATTGCCAGACATTGGCCGCCCGGTGC
CGTTTCTGCCGCTGGAATATAAGGAACTGGTGATCGGGTTTGGCGACAGTGGCTATGTGATGCTCTACCGCCACGACCGG
GAAATGGACCAGATTGTGATCGTCACCGTCAGGCATCAGAAAGAATCCGGGTATCCGGGGGCAGACAGCCTCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT152832 WP_011860336.1 NZ_CP050400:c3263707-3263462 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT152832 NZ_CP066537:c9915-9637 [Klebsiella pneumoniae]
ATGTCATCAGCAACATCCATCAGGCTCGATGAAGAACTTAAGGACCGGCTGAAAACGCTGGCCGATGACCGGCACCGCTC
AGCGCACGCGCTAATGCTGGAGGCAATCACCGAATACATCGACCGGGAAGAGAAGCGCAGCCAGTACCTGCGGGACGGAC
AGGCCGCATGGCAGCACTATCAGGAAACGGGTCTGCACCTTACTGCGGAAGAAGCGGAAGCCTGGATAAGTACCTGGGGA
ACTGAGAACGAGCAGGATGCTCCGCCATGCCACAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References