Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3460267..3460412 Replicon chromosome
Accession NZ_CP050376
Organism Klebsiella pneumoniae strain 51015

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3460274..3460376 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3460267..3460412 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB813_RS16900 3455798..3457231 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HB813_RS16905 3457347..3457586 + 240 WP_002911393.1 YebV family protein -
HB813_RS16910 3457684..3457875 + 192 WP_002911395.1 YebW family protein -
HB813_RS16915 3457872..3458525 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
HB813_RS16920 3458682..3459650 + 969 WP_004151446.1 VirK/YbjX family protein -
HB813_RS16925 3459755..3459898 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3460267..3460412 + 146 - - Antitoxin
- 3460274..3460376 - 103 - - Toxin
HB813_RS16930 3460535..3460873 - 339 WP_002911404.1 YebY family protein -
HB813_RS16935 3460890..3461759 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HB813_RS16940 3461763..3462137 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HB813_RS16945 3462250..3462480 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HB813_RS16950 3462559..3463218 + 660 WP_020324964.1 exodeoxyribonuclease X -
HB813_RS16955 3463222..3465282 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T152772 NZ_CP050376:c3460376-3460274 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT152772 NZ_CP050376:3460267-3460412 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References