Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3880063..3880207 | Replicon | chromosome |
| Accession | NZ_CP050371 | ||
| Organism | Klebsiella pneumoniae strain 50595 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3880069..3880171 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3880063..3880207 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HB637_RS19475 | 3875836..3876117 | + | 282 | WP_032419786.1 | hypothetical protein | - |
| HB637_RS19480 | 3876127..3876555 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| HB637_RS19485 | 3876805..3878310 | - | 1506 | WP_060544606.1 | hypothetical protein | - |
| HB637_RS19490 | 3879099..3879578 | - | 480 | WP_032419797.1 | lysis protein | - |
| HB637_RS19495 | 3879577..3879936 | + | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| - | 3880063..3880207 | + | 145 | - | - | Antitoxin |
| - | 3880069..3880171 | - | 103 | - | - | Toxin |
| HB637_RS19500 | 3880330..3880668 | - | 339 | WP_002911404.1 | YebY family protein | - |
| HB637_RS19505 | 3880685..3881554 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| HB637_RS19510 | 3881558..3881932 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HB637_RS19515 | 3882045..3882275 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HB637_RS19520 | 3882354..3883013 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HB637_RS19525 | 3883017..3885077 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T152743 NZ_CP050371:c3880171-3880069 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT152743 NZ_CP050371:3880063-3880207 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
