Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022871..2023016 | Replicon | chromosome |
| Accession | NZ_CP050348 | ||
| Organism | Klebsiella pneumoniae strain ZRKP02 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022907..2023009 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022871..2023016 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HB787_RS09920 | 2018001..2020061 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HB787_RS09925 | 2020065..2020724 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HB787_RS09930 | 2020803..2021033 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HB787_RS09935 | 2021146..2021520 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HB787_RS09940 | 2021524..2022393 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| HB787_RS09945 | 2022410..2022748 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2022871..2023016 | - | 146 | - | - | Antitoxin |
| - | 2022907..2023009 | + | 103 | - | - | Toxin |
| HB787_RS09950 | 2023384..2023527 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| HB787_RS09955 | 2023632..2024600 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| HB787_RS09960 | 2024757..2025410 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| HB787_RS09965 | 2025407..2025598 | - | 192 | WP_002911395.1 | YebW family protein | - |
| HB787_RS09970 | 2025696..2025935 | - | 240 | WP_002911393.1 | YebV family protein | - |
| HB787_RS09975 | 2026051..2027484 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T152666 NZ_CP050348:2022907-2023009 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT152666 NZ_CP050348:c2023016-2022871 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
