152643

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018814..2018959 Replicon chromosome
Accession NZ_CP050342
Organism Klebsiella pneumoniae strain ZRKP03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018850..2018952 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018814..2018959 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB788_RS09905 2013944..2016004 + 2061 WP_004151449.1 oligopeptidase B -
HB788_RS09910 2016008..2016667 - 660 WP_002911407.1 exodeoxyribonuclease X -
HB788_RS09915 2016746..2016976 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HB788_RS09920 2017089..2017463 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HB788_RS09925 2017467..2018336 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HB788_RS09930 2018353..2018691 + 339 WP_002911404.1 YebY family protein -
- 2018814..2018959 - 146 - - Antitoxin
- 2018850..2018952 + 103 - - Toxin
HB788_RS09935 2019327..2019470 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HB788_RS09940 2019575..2020543 - 969 WP_004151446.1 VirK/YbjX family protein -
HB788_RS09945 2020700..2021353 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HB788_RS09950 2021350..2021541 - 192 WP_002911395.1 YebW family protein -
HB788_RS09955 2021639..2021878 - 240 WP_002911393.1 YebV family protein -
HB788_RS09960 2021994..2023427 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T152643 NZ_CP050342:2018850-2018952 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT152643 NZ_CP050342:c2018959-2018814 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References