Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pasABC/RelE-HTH |
Location | 3447150..3447630 | Replicon | chromosome |
Accession | NZ_CP050308 | ||
Organism | Rhizobium lusitanum strain 629 |
Toxin (Protein)
Gene name | pasB | Uniprot ID | - |
Locus tag | HB780_RS30385 | Protein ID | WP_183691857.1 |
Coordinates | 3447358..3447630 (+) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | pasA | Uniprot ID | - |
Locus tag | HB780_RS30380 | Protein ID | WP_183697637.1 |
Coordinates | 3447150..3447374 (+) | Length | 75 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HB780_RS30350 | 3442508..3443638 | + | 1131 | WP_183691846.1 | site-specific DNA-methyltransferase | - |
HB780_RS30355 | 3443818..3444183 | - | 366 | WP_183691848.1 | nuclear transport factor 2 family protein | - |
HB780_RS30360 | 3444188..3444802 | - | 615 | WP_183691850.1 | HAD family phosphatase | - |
HB780_RS30365 | 3444820..3445929 | - | 1110 | WP_183691851.1 | A/G-specific adenine glycosylase | - |
HB780_RS30370 | 3446042..3446494 | + | 453 | WP_183691853.1 | hypothetical protein | - |
HB780_RS30375 | 3446553..3447071 | + | 519 | WP_183691855.1 | DUF721 domain-containing protein | - |
HB780_RS30380 | 3447150..3447374 | + | 225 | WP_183697637.1 | TraY domain-containing protein | Antitoxin |
HB780_RS30385 | 3447358..3447630 | + | 273 | WP_183691857.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HB780_RS30390 | 3447819..3448556 | + | 738 | WP_183691858.1 | DsbA family protein | - |
HB780_RS30395 | 3448745..3452206 | + | 3462 | WP_183691860.1 | chromosome segregation protein SMC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10687.37 Da Isoelectric Point: 10.5728
>T152496 WP_183691857.1 NZ_CP050308:3447358-3447630 [Rhizobium lusitanum]
MAWKVEFQRPAERELEKLGHETARRILKFLHERVAKLDNPRSIGEALKGSELGDFWKYRVGDYRVIAHIEDSAIRILIVR
VGNRREVYRK
MAWKVEFQRPAERELEKLGHETARRILKFLHERVAKLDNPRSIGEALKGSELGDFWKYRVGDYRVIAHIEDSAIRILIVR
VGNRREVYRK
Download Length: 273 bp
>T152496 NZ_CP066229:1282127-1282309 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8553.71 Da Isoelectric Point: 4.5702
>AT152496 WP_183697637.1 NZ_CP050308:3447150-3447374 [Rhizobium lusitanum]
MLALRLPPEIEARLDELAKRTGRSKSFYAREAILEHLDDLEDIYLAEKRLEEFRRGESDTVSLAELMARYGVEG
MLALRLPPEIEARLDELAKRTGRSKSFYAREAILEHLDDLEDIYLAEKRLEEFRRGESDTVSLAELMARYGVEG
Download Length: 225 bp
>AT152496 NZ_CP066229:1282402-1282806 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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