Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2917080..2917714 Replicon chromosome
Accession NZ_CP050308
Organism Rhizobium lusitanum strain 629

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HB780_RS27775 Protein ID WP_183690987.1
Coordinates 2917080..2917475 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HB780_RS27780 Protein ID WP_183690989.1
Coordinates 2917472..2917714 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB780_RS27745 2912086..2912532 + 447 WP_183697537.1 nuclear transport factor 2 family protein -
HB780_RS27750 2912614..2913378 - 765 WP_183690977.1 SDR family oxidoreductase -
HB780_RS27755 2913498..2914403 + 906 WP_183690978.1 LysR family transcriptional regulator -
HB780_RS27760 2914404..2915279 - 876 WP_183690981.1 LysR family transcriptional regulator -
HB780_RS27765 2915375..2916658 + 1284 WP_183690983.1 MFS transporter -
HB780_RS27770 2916682..2917083 + 402 WP_183690985.1 VOC family protein -
HB780_RS27775 2917080..2917475 - 396 WP_183690987.1 type II toxin-antitoxin system VapC family toxin Toxin
HB780_RS27780 2917472..2917714 - 243 WP_183690989.1 antitoxin Antitoxin
HB780_RS27785 2917783..2918461 - 679 Protein_2765 hypothetical protein -
HB780_RS27790 2918532..2920193 - 1662 WP_183690990.1 urocanate hydratase -
HB780_RS27795 2920217..2920546 - 330 WP_183690992.1 TfoX/Sxy family protein -
HB780_RS27800 2920562..2921662 - 1101 WP_183690994.1 DUF917 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

SpoVT-AbrB domain

(7-42)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14706.89 Da        Isoelectric Point: 6.8818

>T152495 WP_183690987.1 NZ_CP050308:c2917475-2917080 [Rhizobium lusitanum]
VKYLLDSNAVIALMKSHSGFVAEIRKHKPQDFAIPAIVAHELFYGAYKGQRVVDNLARVDALQFETLDFDREDARKAGEI
RAALAIIGTPIGAYDVLIAGQAVARDLILITHNVREFQRVKNLRFEDWETA

Download         Length: 396 bp

>T152495 NZ_CP066229:450280-450669 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9302.45 Da        Isoelectric Point: 4.2584

>AT152495 WP_183690989.1 NZ_CP050308:c2917714-2917472 [Rhizobium lusitanum]
MDTAKIFWSGRSQAVRLPKEFRFDTDAVRIRRQGQAIILEPIVEDWNWLEAVTGPVDQDFAEAATEQPVEQERPELDIFK

Download         Length: 243 bp

>AT152495 NZ_CP066229:450016-450273 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References