Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/Phd-LOTUS_5_Limkain_b1
Location 1377248..1377912 Replicon chromosome
Accession NZ_CP050308
Organism Rhizobium lusitanum strain 629

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HB780_RS20430 Protein ID WP_183695703.1
Coordinates 1377248..1377502 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HB780_RS20435 Protein ID WP_183695706.1
Coordinates 1377502..1377912 (+) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB780_RS20410 1372763..1373188 + 426 WP_183695691.1 hypothetical protein -
HB780_RS20415 1373401..1375200 + 1800 WP_183695694.1 DUF4209 domain-containing protein -
HB780_RS20420 1375455..1376066 - 612 WP_183695697.1 alpha/beta hydrolase -
HB780_RS20425 1376082..1377014 - 933 WP_183695700.1 VOC family protein -
HB780_RS20430 1377248..1377502 + 255 WP_183695703.1 type II toxin-antitoxin system Phd/YefM family antitoxin Toxin
HB780_RS20435 1377502..1377912 + 411 WP_183695706.1 type II toxin-antitoxin system VapC family toxin Antitoxin
HB780_RS20440 1377906..1378607 - 702 WP_183695709.1 uracil-DNA glycosylase -
HB780_RS20445 1378697..1380247 - 1551 WP_183695712.1 FAD-dependent monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)

Antitoxin

PIN domain

(2-122)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9332.44 Da        Isoelectric Point: 4.3286

>T152493 WP_183695703.1 NZ_CP050308:1377248-1377502 [Rhizobium lusitanum]
MDWPLQDAKNQFSKVVQKARSEGPQTVTLRGERAAVVLSAEDYDALRAGKPSLVDDLLSEPIWDDELADAVMTRDKTPSR
DVAF

Download         Length: 255 bp

>T152493 NZ_CP066219:c1315821-1315075 [Bacillus siamensis]
ATGCTCATGTTTTTTCAGATCATGGTGTGGACGATGGCCGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTTCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCTCTTATTGATGCGTTT
ATCTTTTTGAGCGCATATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGAGGGAGATTTTGGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCAGAAGGCATCAGCAGACTGCTGGCCGCTTATGCAGAAAAAATGAATGTCACGGCTTCATTG
TGCGACTATTCGGCACAGTCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGCCTTAA
CCGAAAAGACGTCTACTATGATCAAAAGGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGGACCGCCATTATGTGATCA
AACTGACGTCAGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACAAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGATAA

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15190.30 Da        Isoelectric Point: 6.6470

>AT152493 WP_183695706.1 NZ_CP050308:1377502-1377912 [Rhizobium lusitanum]
MYLVDTNVVSEARRGTVEAISWLRSVEPSTVYLSVITLGEVMRGIALKRRSDPRAATHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRLAALRPRGEADGLIAATAIVHDLIVVTRNTKDFDDTGVSIVDPWDQASH

Download         Length: 411 bp

>AT152493 NZ_CP066219:c1315075-1314905 [Bacillus siamensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGCTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAACGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References