Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1463119..1463651 Replicon plasmid p_1
Accession NZ_CP050307
Organism Rhizobium lusitanum strain 629

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HB780_RS09770 Protein ID WP_183687267.1
Coordinates 1463119..1463412 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HB780_RS09775 Protein ID WP_183687269.1
Coordinates 1463409..1463651 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB780_RS09750 1458667..1459470 + 804 WP_183687263.1 phosphonoacetaldehyde hydrolase -
HB780_RS09755 1459687..1460831 + 1145 Protein_1346 IS3 family transposase -
HB780_RS09760 1460929..1461516 + 588 WP_183687265.1 hypothetical protein -
HB780_RS09765 1461748..1462785 + 1038 WP_183686283.1 IS110 family transposase -
HB780_RS09770 1463119..1463412 - 294 WP_183687267.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HB780_RS09775 1463409..1463651 - 243 WP_183687269.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HB780_RS09780 1463885..1464369 + 485 Protein_1351 aldehyde dehydrogenase family protein -
HB780_RS09785 1464466..1465233 - 768 WP_183687271.1 ABC transporter permease -
HB780_RS09790 1465233..1465988 - 756 WP_183687273.1 ABC transporter permease subunit -
HB780_RS09795 1465985..1466767 - 783 WP_183687275.1 ABC transporter ATP-binding protein -
HB780_RS09800 1466764..1467492 - 729 WP_183687277.1 FCD domain-containing protein -
HB780_RS09805 1467489..1468427 - 939 WP_183687279.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..2402091 2402091


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(12-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11194.75 Da        Isoelectric Point: 5.1532

>T152492 WP_183687267.1 NZ_CP050307:c1463412-1463119 [Rhizobium lusitanum]
MSFKLSVEAEEDIIAIAEQGVRMFAAGQAKRYHDELFALFDLIAVNPRIARERDEIDPPVRIHPFKAHLIVYRIEDDETI
FVIRIGHGHEDWASHSI

Download         Length: 294 bp

>T152492 NZ_CP066219:472074-472424 [Bacillus siamensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAGAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8823.91 Da        Isoelectric Point: 9.7765

>AT152492 WP_183687269.1 NZ_CP050307:c1463651-1463409 [Rhizobium lusitanum]
MATMNVSLPGPMKDWVEAQARTGRYSNASDYVRDLIRRDQTRNDKIAAMQSFVEAGLQSGVGIRSKDELFAEATARASKS

Download         Length: 243 bp

>AT152492 NZ_CP066219:471787-472068 [Bacillus siamensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCACAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAACATTTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References