Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 1614835..1616317 Replicon chromosome
Accession NZ_CP050301
Organism Phyllobacterium sp. 628

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag HB779_RS09490 Protein ID WP_188345461.1
Coordinates 1615445..1616317 (+) Length 291 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag HB779_RS09485 Protein ID WP_188345460.1
Coordinates 1614835..1615452 (+) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB779_RS09470 1610609..1612744 - 2136 WP_188345458.1 ParB/RepB/Spo0J family partition protein -
HB779_RS09475 1612920..1614114 - 1195 Protein_1582 DUF932 domain-containing protein -
HB779_RS09480 1614310..1614549 - 240 WP_210302626.1 XRE family transcriptional regulator -
HB779_RS09485 1614835..1615452 + 618 WP_188345460.1 transcriptional regulator Antitoxin
HB779_RS09490 1615445..1616317 + 873 WP_188345461.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HB779_RS09495 1616378..1616971 + 594 WP_188345462.1 hypothetical protein -
HB779_RS09500 1617128..1618543 + 1416 WP_188345463.1 N-6 DNA methylase -
HB779_RS09505 1618540..1620093 + 1554 WP_188345464.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 291 a.a.        Molecular weight: 32360.09 Da        Isoelectric Point: 6.2902

>T152488 WP_188345461.1 NZ_CP050301:1615445-1616317 [Phyllobacterium sp. 628]
MAKEIKNIGASVRARLLQVSKTSGQTFDLVLTRFALERLLFRLSQSPHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSAEPMLATFRDILAQGAADGVEFDVDALRVDRIREEREYGGLRLRTTASIGGARISLTIDIGFGDAVEPGAEELDYPS
MLDFPMPRLRGYARETVIAEKFQAMVALGRANTRMKDFYDIWILSRSFTFDDDRLPRAIAATFARRGTAIPQDLPDALTS
VFAEDAQKKRQWRAFVEGVVAHDPGELAVVIKDIATFLMPRVTSTRSLGQ

Download         Length: 873 bp

>T152488 NZ_CP066218:1050421-1050828 [Mycolicibacterium sp. LJ126]
ATGTCGTCGCCGTCCCCGCGGAAGCAGGTGGTCATCGACGCGAGTGCCATGGTCGACCTCCTCGCTCGCGCGGGTGATCG
GTACTCCGCGGTGCGAGCGCGACTGGCGCGGACGGTGATGCATGCACCGGCCCACTTCGATGCCGAAGTGCTTTCGGCGC
TTGGGCGACTGCAGCGTGCCGGCGCGCTCACCGTCGTGGAGGTCGATGCAGCACTTGACGAACTCCGACGGGCGCCGGTG
ACTCGGCACGATCTCACGCCCCTGGTGGTCGGAGCGTGGGCGCGCCGCGACACGCTCCGGCTGGCCGATGCGCTCTACGT
CGAGCTGGCAGATACCGCTGGTCTGACGTTGCTGACGACGGACCAGAGGCTGGCACGTGCTTGGCCTTCGGCTGACGTGA
TCATCTGA

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22309.78 Da        Isoelectric Point: 10.3271

>AT152488 WP_188345460.1 NZ_CP050301:1614835-1615452 [Phyllobacterium sp. 628]
VPPSMSQRQIAHTVLTARGISRLAELREAGVTAATMSRMERDGEVLRLARGLYQLSDAPLDVHHSLAEAAKRIPKGVVCL
VSALAFHGLTDQLPRQVWLAVGQKDWSPKAEGTPIRLVRFTDRLLTEGVETHAVEGVAVKVFGVAKTVADCFRYRNKIGL
SVAIEGLQEALRQRKTTPGEIARQAERGTVATIVRPYLEALTANG

Download         Length: 618 bp

>AT152488 NZ_CP066218:1050200-1050418 [Mycolicibacterium sp. LJ126]
ATGGCCCGGCTGAACGTGTATGTCCCCGATGATTTAGCGGAGCACGCCAGGGCGCGTGGGTTGAATGTCTCGGCGCTGAC
TCAAGCCGCCATTCGCGCAGAACTGGAGGATGCCGCGACCGACACGTGGCTCGAGAGCTTGGACGCCAAGAGCACCGGTG
CGCGGCATGGCGACGTGTTGGCTGCCATCGACGCCGCCCGCGACGAACTGGGAACATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References