Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 614675..615465 Replicon plasmid p_1
Accession NZ_CP050299
Organism Mesorhizobium huakuii strain 583

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag HB778_RS40620 Protein ID WP_183465707.1
Coordinates 614675..615193 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag HB778_RS40625 Protein ID WP_183455111.1
Coordinates 615190..615465 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HB778_RS40605 610042..611400 + 1359 WP_183465705.1 type IV secretion system protein VirB10 -
HB778_RS40610 611360..612417 + 1058 Protein_556 P-type DNA transfer ATPase VirB11 -
HB778_RS40615 612395..614530 + 2136 WP_183465706.1 type IV secretory system conjugative DNA transfer family protein -
HB778_RS40620 614675..615193 - 519 WP_183465707.1 GNAT family N-acetyltransferase Toxin
HB778_RS40625 615190..615465 - 276 WP_183455111.1 DUF1778 domain-containing protein Antitoxin
HB778_RS40630 615821..616009 + 189 WP_183455110.1 type II toxin-antitoxin system HicA family toxin -
HB778_RS40635 616015..616416 + 402 WP_183455109.1 type II toxin-antitoxin system HicB family antitoxin -
HB778_RS40640 616829..619156 - 2328 WP_183465708.1 relaxase/mobilization nuclease domain-containing protein -
HB778_RS40645 619153..619569 - 417 WP_183455107.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..686467 686467


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(7-88)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 18384.97 Da        Isoelectric Point: 9.6395

>T152481 WP_183465707.1 NZ_CP050299:c615193-614675 [Mesorhizobium huakuii]
VSSVIWQEVPISKQHDRAAFNCGDADLNTYLQRFARQNHESGGAKTFVAVTAEDSSHILGFYSLSPASMDYARTPTVARR
GLGRNNAPVYRLGRLAVDRKIQGRGLGGGLLLAAGRRCIAVAQEVGGVALLIDAKGDQAARWYEGYGAVRLDDAPLYLVL
PFAAIAKAIAAI

Download         Length: 519 bp

>T152481 NZ_CP066203:c492609-492313 [Methylacidimicrobium sp. B4]
TTGATCGTTGGCTTTCGGGATGAATGGTTGCGGGCCTTCTTCGTGGACGACGCCCAATCCCGCAACATCCCATCCGACCT
GGAAGCCAGGTTGTTCCGCAAGCTCCAGATGATCGACGACGCCACGACCGATCACGACTTGCGTGTGCCGCCCAGCAACC
ATTTCGAGAAGCTGAAAGGCAATCTGGCAGGCCTCCACTCGATCCGCGTCAGCAAGCAATACCGGCTGGTCTTTCGCTCG
GATGGTGAACGCGGCGAGGCCGACGGCATCTATCTGGACGATCACAGCTACCGATGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9841.23 Da        Isoelectric Point: 8.9951

>AT152481 WP_183455111.1 NZ_CP050299:c615465-615190 [Mesorhizobium huakuii]
MPRNVSDNGRIDFRIPPEAKAVIARAAALSNVGLTEFVTRSALRDAQAAIERAEHLALSERDSLRVLDLLENPPAPTDRL
IRAAKAGQTLA

Download         Length: 276 bp

>AT152481 NZ_CP066203:c492298-491990 [Methylacidimicrobium sp. B4]
ATGCTGACCACCAAGCGCAAGCCGGCGAGCGTCGGCGAGATACTGACTGAAGAGTTCATGGAGCCGATGGGGCTGACGCA
GGGAGCGCTCGCCGAGGCGATGGGCGTCCAGCGCAAACACGTCAACGAATTGTGCAGCAACCGCAGGAACGTGACGGCCG
CGACGGCGCTGATCCTGGCCCGTGTGTTCGGCAATAGCCCCGACTTCTGGCTCAACGTGCAGCGACGCAACGATCTTTGG
GAGGTGATGAACACACCCAAGGAGCGCGCAAGGGTCGAGCGCGCGCGCCCCGTGAAGAAGGCTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References