Detailed information of TA system TA152479

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yafQ-relB/YafQ-RelB
• Location: 4767730..4768262
• Replicon: chromosome
• Accession: NZ_CP050296
• Organism: Mesorhizobium huakuii strain 583

Toxin (Protein)

• Gene name: yafQ
• Uniprot ID: -
• Locus tag: HB778_RS22935
• Protein ID: WP_183457207.1
• Coordinates: 4767730..4768002 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HB778_RS22940
• Protein ID: WP_183457209.1
• Coordinates: 4768005..4768262 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HB778_RS22920	4763960..4765471	+	1512	WP_183457201.1	sugar ABC transporter ATP-binding protein	-
HB778_RS22925	4765553..4766548	+	996	WP_183457203.1	ABC transporter permease	-
HB778_RS22930	4766596..4767648	+	1053	WP_183457205.1	substrate-binding domain-containing protein	-
HB778_RS22935	4767730..4768002	-	273	WP_183457207.1	type II toxin-antitoxin system YafQ family toxin	Toxin
HB778_RS22940	4768005..4768262	-	258	WP_183457209.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
HB778_RS22945	4768412..4770466	-	2055	WP_183457210.1	bifunctional aldolase/short-chain dehydrogenase	-
HB778_RS22950	4770553..4771518	-	966	WP_183457212.1	sugar-binding transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (7-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10423.96 Da
• Isoelectric Point: 10.0891

>T152479 WP_183457207.1 NZ_CP050296:c4768002-4767730 [Mesorhizobium huakuii]
MPAPIHSGQFRRDVKRMEKRGKNLGKLRDLLGLFIAGRELPATYKDHPLRGDWKGFRDAHIEPDWLLIYRVVGDELQLAR
TGSHSDLFNE

Nucleotide

• Length: 273 bp

>T152479 NZ_CP066194:c3272272-3271532 [Bacillus cytotoxicus]
TTGACTGTCACTAGCGTTCGAATTGGCTTGTTTTTTCTTGTAATCTTTTTTTTATTTCTTATTTTCTTTTATTGGAGAAA
TGAAGAACGATACGAGGAAAGAAAACAACTTATTCGAAAGACGTGGTATGGTTTATTTATTACATCAGTCACAATGTATT
TCATGATGAAAGGAATTGATTTAACCCTCTGGAAACATATTTTAATGGTTGTTGCGATGGTTGTATTTGTTGATATTGCA
TTTATTTTAACGCCAAATATTTCGGAAATCTGGGGCGCAAAGTTTAGTGATATTGGTAAGACAGTTCAATCGATTAAACG
ATCGCTTATTGCTTCAAAAGCAAGAGGAGAAATATATACAACACTTATTCAAAATGTAAATCCAGCTGCATTTGGTACGA
TGGAATGGGAAACAGATGCTGAGTATGCACGCAGTTTAAATGCTTTTCTTGATACGTATGCTGAAAAAATAGGTGCGAAA
ATTGTAGTATTTGTCACAGAAGAGGAATTAAATACAAACTTCCGAGGTGTTCGATCTCAATTTAGTATTACAGTATCACC
CGAATCTATTGAACAACTGAATGAGCAAAAAGCAGTTCAAATTGAAAATGTTGGAATTATACCAGCGAAAATAATAAAAG
ACGTTTATATTATTATGGATGGACAAAAAAATAATTTGCAAGATCGTGACTTTGAAAATGTATATAATTTAACAATACAT
CATAGTTACTTTTGTAAGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9135.61 Da
• Isoelectric Point: 9.9482

>AT152479 WP_183457209.1 NZ_CP050296:c4768262-4768005 [Mesorhizobium huakuii]
MATDSVVRARIDTATKDQATEALAAMGLSVSDAIRLLLVRVAADKEFPFPVKVPNATTRKAMAELEKGKGKRFASADELF
KDLGL

Nucleotide

• Length: 258 bp

>AT152479 NZ_CP066194:c3271408-3271280 [Bacillus cytotoxicus]
GTGTTAAAAGAATATAGCAATGATTTCTTTAAAGACGAAGCTGAGGATACAACAGATTTTTCTTTAATAAAAGGAGATAC
AATGCAGCAAGTGGAAGAATTAGAAGAAGAATTGAAAAGAAGAGGATAA