Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 201333..201984 | Replicon | chromosome |
Accession | NZ_CP050267 | ||
Organism | Salinivibrio costicola strain M318 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | HBA18_RS14355 | Protein ID | WP_167315412.1 |
Coordinates | 201580..201984 (+) | Length | 135 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | A0A1V3HTW4 |
Locus tag | HBA18_RS14350 | Protein ID | WP_069363032.1 |
Coordinates | 201333..201566 (+) | Length | 78 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HBA18_RS14330 | 196822..199269 | + | 2448 | WP_167315162.1 | DUF2309 domain-containing protein | - |
HBA18_RS14335 | 199278..200249 | + | 972 | WP_139130769.1 | threonylcarbamoyl-AMP synthase | - |
HBA18_RS14340 | 200242..200661 | - | 420 | WP_167315163.1 | PaaI family thioesterase | - |
HBA18_RS14345 | 200654..201163 | - | 510 | WP_167315164.1 | hypothetical protein | - |
HBA18_RS14350 | 201333..201566 | + | 234 | WP_069363032.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
HBA18_RS14355 | 201580..201984 | + | 405 | WP_167315412.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
HBA18_RS14360 | 202016..202297 | - | 282 | WP_021023566.1 | DUF134 domain-containing protein | - |
HBA18_RS14365 | 202425..203873 | - | 1449 | WP_167315165.1 | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | - |
HBA18_RS14370 | 203885..204610 | - | 726 | WP_167315166.1 | 6-phosphogluconolactonase | - |
HBA18_RS14375 | 204607..206109 | - | 1503 | WP_077662404.1 | glucose-6-phosphate dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14728.17 Da Isoelectric Point: 9.2145
>T152447 WP_167315412.1 NZ_CP050267:201580-201984 [Salinivibrio costicola]
MLDTCICSFIMREQPKAVLKKLHTVVGNQHRIVISAITYQEMQYGLLGKKASPKHAVLVDAFLQRIDEILPWDKAAVDAT
TAVKRNLMNKGKGTPIGGNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWA
MLDTCICSFIMREQPKAVLKKLHTVVGNQHRIVISAITYQEMQYGLLGKKASPKHAVLVDAFLQRIDEILPWDKAAVDAT
TAVKRNLMNKGKGTPIGGNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWA
Download Length: 405 bp
>T152447 NZ_CP066167:c736672-736421 [Spongiibacter sp. CSC3.9]
ATGGACAGTATAAGCTATACCGCCGCCAGGAGCAACTTGGCGAAAACTATGGAGCAGGTCTGTAACGACCATGCGCCCAT
TGCTATTACCCGCAAGGGCGAAGGTGCCGTTGTGATGATTTCTATGGACGACTACCAAGCCTTGGAAGAAACGGCATATC
TGCTTCGGAGCCCCAAAAATACCCGACGCCTGATCGAGTCTATTGCCGAGCTTGAGGACGGCAAAGGCCAAGAAAAGGAA
TTGATTGAGTGA
ATGGACAGTATAAGCTATACCGCCGCCAGGAGCAACTTGGCGAAAACTATGGAGCAGGTCTGTAACGACCATGCGCCCAT
TGCTATTACCCGCAAGGGCGAAGGTGCCGTTGTGATGATTTCTATGGACGACTACCAAGCCTTGGAAGAAACGGCATATC
TGCTTCGGAGCCCCAAAAATACCCGACGCCTGATCGAGTCTATTGCCGAGCTTGAGGACGGCAAAGGCCAAGAAAAGGAA
TTGATTGAGTGA
Antitoxin
Download Length: 78 a.a. Molecular weight: 9013.13 Da Isoelectric Point: 4.8668
>AT152447 WP_069363032.1 NZ_CP050267:201333-201566 [Salinivibrio costicola]
MRTISIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPSWLSFGELEKADSDFMTHREELIKDEGRFNFD
MRTISIFKNGKNQAVRLPKDFEFDGVNELEIHKEGDVITLRPARPSWLSFGELEKADSDFMTHREELIKDEGRFNFD
Download Length: 234 bp
>AT152447 NZ_CP066167:c736424-736170 [Spongiibacter sp. CSC3.9]
GTGAAGTTAATTTTTGCAGAGAAGGCATGGGAGGATTACCTGTACTGGCAAAAAACGGACAAACAGACACTGAAACGTAT
TAATACCCTTATCAAGGAAATCAAACGAGAACCATTCGAAGGCATTGGAAAGCCAGAGCCGCTCAAACATGCCCTTTCGG
GGTATTGGTCTCGAAGGATTAACGATGAGCACCGAATGGTTTATAAAATTCATCAAGATTCCCTGCTTATTGCCCAACTT
CGCTACCACTACTGA
GTGAAGTTAATTTTTGCAGAGAAGGCATGGGAGGATTACCTGTACTGGCAAAAAACGGACAAACAGACACTGAAACGTAT
TAATACCCTTATCAAGGAAATCAAACGAGAACCATTCGAAGGCATTGGAAAGCCAGAGCCGCTCAAACATGCCCTTTCGG
GGTATTGGTCTCGAAGGATTAACGATGAGCACCGAATGGTTTATAAAATTCATCAAGATTCCCTGCTTATTGCCCAACTT
CGCTACCACTACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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