Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 1921832..1922354 Replicon chromosome
Accession NZ_CP050171
Organism Serratia fonticola strain CPSE11

Toxin (Protein)


Gene name relE Uniprot ID A0A0U4JRE1
Locus tag HAP32_RS08890 Protein ID WP_021806920.1
Coordinates 1922073..1922354 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I0CUG0
Locus tag HAP32_RS08885 Protein ID WP_071682601.1
Coordinates 1921832..1922083 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAP32_RS08875 1919450..1920907 - 1458 WP_071682599.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
HAP32_RS08880 1921114..1921767 + 654 WP_071682600.1 Qnr family pentapeptide repeat protein -
HAP32_RS08885 1921832..1922083 + 252 WP_071682601.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HAP32_RS08890 1922073..1922354 + 282 WP_021806920.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HAP32_RS08895 1922523..1923158 + 636 WP_166733461.1 glutathione transferase -
HAP32_RS08900 1923269..1924723 - 1455 WP_021180637.1 NAD-dependent succinate-semialdehyde dehydrogenase -
HAP32_RS08905 1924736..1926001 - 1266 WP_166733462.1 4-aminobutyrate--2-oxoglutarate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10991.89 Da        Isoelectric Point: 10.6704

>T152347 WP_021806920.1 NZ_CP050171:1922073-1922354 [Serratia fonticola]
MTYKLKFEKRALKEWEKLGYPVREQLKKKLAERLENPHVPASRLSGRPNRYKIKLRSSGYRLVYEVRDNEIVLLVIAVGK
RAGEEVYFAADKR

Download         Length: 282 bp

>T152347 NZ_CP066125:c3640248-3639595 [Aeromonas veronii]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGGAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAATCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGCCAGCAGCAAAATCCGCACTGGGTGCATATCGGGCTGTCGGAGCTGA
TTGCCAAACGTGCTCGCCATCCGGTGCCACTGGCCCCTTACGGCGTACTGAATGACTATGTGCCCTTTTACTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACGCGGGGCGAGGTGTTCCCCAGCGTGAAAATGATGAAATATTGATCCTGGTTTC
CAGTCTGCATCGCATGGCCGAACTGGGGTTGCCGTTTGTGTTTACCGATAGCCATGCTTATTACCAGTGGGCCAATTTCT
ATGACGACCTTGGCGAATTGGGACGGATTGATTGGCCTCTTCTGCAGCGCCGTGATTTCAAGCGTGACCCGGATGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAAGCCTTGATCTATCAGCATTGTCCCATCGAGGCGTTGCAGGGCGTGGTGTGTTA
CAACGAAGAAATAAAGAACAGCGTGGAACAATGCATGAATCGGGTAGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.38 Da        Isoelectric Point: 3.8427

>AT152347 WP_071682601.1 NZ_CP050171:1921832-1922083 [Serratia fonticola]
MAFQILTTIAASITDLKKNPMGTVADGEGEAVAILNRNEPAFYCVPPELYAYYRELAEDAELNRIADERMEDAEFVSVNL
NDL

Download         Length: 252 bp

>AT152347 NZ_CP066125:c3639598-3638534 [Aeromonas veronii]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGCCGAAGTACTGGTGAATACCGTCAACACGGTTGGTGTCAT
GGGGAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATATGCGTGCCTATGCAGAGGCGTGCAAACAGGGCG
AGGTCGTCACCGGTAAGATGTTTATTACCCAAACGGGTGAGCTGCTAGGGCCGCGCTGGATCGTGAACTTTCCGACCAAA
CAGCACTGGCGTAACCCGGCTCAGATGGCGTGGATCCAGGATGGTTTGCAGGATCTGCGGGCCTGGTTACAAGCTCAGCA
GGTCTCTTCGATTGCCATTCCGCCGCTGGGGGCTGGCAACGGCGGTTTGCCTTGGCCGGAGGTCAAACAGGCGATTGAAA
CGGCATTGGGTGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTAGCCAATACCAAAATGTGGCCAAGCGGGGCGGG
GTAGCGGAGCTGACGCCAGCTCGGGCCTTGATTGCTGAACTGGTGCGTCGCTACTGGTTTTTGGGGATGGAGTGCAGCTT
GTTGGAAATCCAGAAACTAGCCTGGTTTCTGGCTCGGGTCATTGGCCGAAATCCGCAGGGTGATCCGCTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGACCTTATGCTAACAATCTGACTCATTTGCTCAATGCGATGGATGGCAGTTATCTGCAGTCT
GACAAGCGCATTCCGGACAGCAAGCCATTCGATGTCATCTGGTTTAATGAGGCCAAAAAACAAGAGCTTGCCGTTTATCT
CAATACCGAGGCCAAAGCGTTTTTGCCAATACTGGAGCAGACGACCGCGTTGATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTGGATTGGCTGATGGCTAAAGAGGGCTGTGCGCCAACGGTGAGCGCGCTGCGAGAAGGTTTG
CACCGCTGGCCAGCGGGAACCCCGTGGGGGGAGCGTAAGGCGCGGCTGTTTGACGATCGCAGTCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGGTTGGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0U4JRE1

Antitoxin

Source ID Structure

References