Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 424652..425160 Replicon chromosome
Accession NZ_CP050136
Organism Kingella kingae strain ATCC 23332

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HBA47_RS02255 Protein ID WP_019389434.1
Coordinates 424900..425160 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HBA47_RS02250 Protein ID WP_019389435.1
Coordinates 424652..424909 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBA47_RS02235 419661..421391 - 1731 WP_060536984.1 PriCT-2 domain-containing protein -
HBA47_RS02240 421388..423505 - 2118 WP_154699877.1 type IV secretory system conjugative DNA transfer family protein -
HBA47_RS02245 423525..424586 - 1062 WP_019389436.1 P-type DNA transfer ATPase VirB11 -
HBA47_RS02250 424652..424909 + 258 WP_019389435.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
HBA47_RS02255 424900..425160 + 261 WP_019389434.1 Txe/YoeB family addiction module toxin Toxin
HBA47_RS02260 425212..425460 - 249 WP_019389433.1 hypothetical protein -
HBA47_RS02265 425500..426534 - 1035 WP_019389432.1 TrbI/VirB10 family protein -
HBA47_RS02270 426547..427365 - 819 WP_019389431.1 TrbG/VirB9 family P-type conjugative transfer protein -
HBA47_RS02275 427362..428063 - 702 WP_019389430.1 type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10457.92 Da        Isoelectric Point: 5.6906

>T152280 WP_019389434.1 NZ_CP050136:424900-425160 [Kingella kingae]
MRLIFSDDAWQDYVYWQTADRKILKRINLLIQDIQREPFDGIGKPEPLRFNLAGFWSRRIDEEHRLVYAIEDESVLIVSC
RYHYQP

Download         Length: 261 bp

>T152280 NZ_CP050136:424900-425160 [Kingella kingae]
ATGCGACTGATTTTTTCCGATGACGCATGGCAAGACTATGTGTATTGGCAAACCGCAGACCGAAAAATCTTAAAACGCAT
CAATCTGTTAATCCAAGACATTCAACGAGAACCGTTTGATGGCATCGGCAAACCGGAACCTTTGCGTTTCAATTTGGCTG
GATTTTGGTCAAGGCGCATTGATGAAGAACATCGCTTAGTCTATGCCATTGAAGATGAAAGTGTTTTAATCGTGTCTTGC
CGTTACCATTATCAACCTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9811.03 Da        Isoelectric Point: 5.1111

>AT152280 WP_019389435.1 NZ_CP050136:424652-424909 [Kingella kingae]
MNTVTYSEVRQNLAKTMQEVVENHEPVLITRAKNEDCVLISLAHYRSLEETAYLLRSPANAAHLQRSIEQLRQNRGTEQE
LIECD

Download         Length: 258 bp

>AT152280 NZ_CP050136:424652-424909 [Kingella kingae]
ATGAATACGGTAACTTATTCAGAAGTAAGACAAAATTTGGCAAAAACCATGCAAGAAGTCGTTGAAAATCATGAACCTGT
GTTGATTACACGCGCCAAAAATGAAGACTGTGTTTTGATTTCATTGGCGCATTACCGTTCTTTGGAGGAAACCGCTTATT
TGTTGCGTTCGCCAGCTAATGCCGCGCATTTGCAACGTTCCATTGAGCAGTTGCGCCAAAATCGCGGTACAGAACAGGAG
CTGATTGAATGCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References