Detailed information of TA system TA152268

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 4017007..4017563
• Replicon: chromosome
• Accession: NZ_CP050115
• Organism: Xanthomonas oryzae pv. oryzae strain K3a

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: HAQ11_RS18900
• Protein ID: WP_027703932.1
• Coordinates: 4017273..4017563 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: HAQ11_RS18895
• Protein ID: WP_011408759.1
• Coordinates: 4017007..4017285 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAQ11_RS18870	4012124..4012729	-	606	Protein_3595	DNA-3-methyladenine glycosylase	-
HAQ11_RS18875	4012831..4013796	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
HAQ11_RS18880	4014377..4015561	+	1185	WP_011408760.1	IS256 family transposase	-
HAQ11_RS18885	4016322..4016522	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
HAQ11_RS23055	4016467..4016811	+	345	WP_199285675.1	hypothetical protein	-
HAQ11_RS23060	4016723..4016926	+	204	WP_199285669.1	hypothetical protein	-
HAQ11_RS18895	4017007..4017285	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
HAQ11_RS18900	4017273..4017563	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HAQ11_RS23065	4017824..4018021	+	198	WP_004541336.1	hypothetical protein	-
HAQ11_RS18910	4018165..4018344	+	180	WP_015463309.1	hypothetical protein	-
HAQ11_RS18925	4019208..4019609	-	402	WP_011259345.1	H-NS histone family protein	-
HAQ11_RS18930	4019831..4020007	+	177	Protein_3606	DUF3606 domain-containing protein	-
HAQ11_RS18935	4020023..4020229	+	207	Protein_3607	hypothetical protein	-
HAQ11_RS18940	4020289..4020626	+	338	Protein_3608	ATP-dependent DNA ligase	-
HAQ11_RS18945	4020702..4021793	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T152268 WP_027703932.1 NZ_CP050115:4017273-4017563 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T152268 NZ_CP066085:c3976138-3975887 [Escherichia fergusonii]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAACGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCCCTGGAAGAGACGGCTTATC
TATTGCGTTCCCCCGCTAATGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT152268 WP_011408759.1 NZ_CP050115:4017007-4017285 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT152268 NZ_CP066085:c3975890-3975636 [Escherichia fergusonii]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACTCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2