Detailed information of TA system TA152267

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 3513053..3514572
• Replicon: chromosome
• Accession: NZ_CP050115
• Organism: Xanthomonas oryzae pv. oryzae strain K3a

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: A0A0K0GMB6
• Locus tag: HAQ11_RS16665
• Protein ID: WP_011259680.1
• Coordinates: 3513649..3514572 (+)
• Length: 308 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: A0A854CLN1
• Locus tag: HAQ11_RS16660
• Protein ID: WP_011409027.1
• Coordinates: 3513053..3513652 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAQ11_RS16620	3508735..3509271	-	537	WP_011409032.1	lipocalin family protein	-
HAQ11_RS16630	3509790..3510008	-	219	Protein_3163	DUF1788 domain-containing protein	-
HAQ11_RS16635	3509989..3510728	-	740	Protein_3164	DUF1819 family protein	-
HAQ11_RS16640	3510778..3511809	+	1032	WP_042465093.1	IS630 family transposase	-
HAQ11_RS16645	3511896..3512351	-	456	Protein_3166	BrxE family protein	-
HAQ11_RS16650	3512398..3512718	-	321	WP_011409028.1	hypothetical protein	-
HAQ11_RS16660	3513053..3513652	+	600	WP_011409027.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
HAQ11_RS16665	3513649..3514572	+	924	WP_011259680.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
HAQ11_RS16670	3514652..3514861	-	210	WP_042465653.1	hypothetical protein	-
HAQ11_RS16675	3514934..3515155	-	222	Protein_3171	hypothetical protein	-
HAQ11_RS16680	3515588..3515830	+	243	WP_011409025.1	hypothetical protein	-
HAQ11_RS16685	3516282..3517247	-	966	Protein_3173	IS1595 family transposase	-
HAQ11_RS16690	3517342..3517830	+	489	WP_011409022.1	hypothetical protein	-
HAQ11_RS16695	3517847..3518379	-	533	Protein_3175	methyltransferase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (41-269)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (7-52)

Sequences

Toxin

Protein

• Length: 308 a.a.
• Molecular weight: 34114.16 Da
• Isoelectric Point: 5.4588

>T152267 WP_011259680.1 NZ_CP050115:3513649-3514572 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Nucleotide

• Length: 924 bp

>T152267 NZ_CP066085:c3975890-3975636 [Escherichia fergusonii]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACTCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22037.74 Da
• Isoelectric Point: 10.1240

>AT152267 WP_011409027.1 NZ_CP050115:3513053-3513652 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Nucleotide

• Length: 600 bp

>AT152267 NZ_CP066085:c3976138-3975887 [Escherichia fergusonii]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAACGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCCCTGGAAGAGACGGCTTATC
TATTGCGTTCCCCCGCTAATGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Structures

Toxin

• AlphaFold DB: A0A0K0GMB6

Antitoxin

• AlphaFold DB: A0A854CLN1