152265

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 1545912..1546262 Replicon chromosome
Accession NZ_CP050115
Organism Xanthomonas oryzae pv. oryzae strain K3a

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag HAQ11_RS07295 Protein ID WP_011257368.1
Coordinates 1545912..1546046 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag HAQ11_RS07300 Protein ID WP_011407410.1
Coordinates 1546110..1546262 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ11_RS07280 1542926..1543948 - 1023 WP_011257371.1 MBL fold metallo-hydrolase -
HAQ11_RS07285 1544001..1545290 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
HAQ11_RS07290 1545459..1545668 - 210 WP_011407411.1 CsbD family protein -
HAQ11_RS07295 1545912..1546046 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
HAQ11_RS07300 1546110..1546262 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
HAQ11_RS07305 1546370..1547293 - 924 WP_011407409.1 arginase -
HAQ11_RS07310 1547615..1548289 + 675 WP_011257366.1 hypothetical protein -
HAQ11_RS07315 1548286..1548525 + 240 WP_011257365.1 hypothetical protein -
HAQ11_RS07320 1548532..1548828 + 297 WP_011257364.1 hypothetical protein -
HAQ11_RS07325 1549308..1549991 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T152265 WP_011257368.1 NZ_CP050115:c1546046-1545912 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T152265 NZ_CP066085:3128694-3128797 [Escherichia fergusonii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT152265 WP_011407410.1 NZ_CP050115:c1546262-1546110 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT152265 NZ_CP066085:c3128835-3128567 [Escherichia fergusonii]
AAAGTCAGCGAATGGAATATTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References