152264

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2930648..2930998 Replicon chromosome
Accession NZ_CP050114
Organism Xanthomonas oryzae pv. oryzae strain K3

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag HAQ10_RS13730 Protein ID WP_011257368.1
Coordinates 2930864..2930998 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag HAQ10_RS13725 Protein ID WP_011407410.1
Coordinates 2930648..2930800 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ10_RS13700 2926919..2927602 - 684 WP_011257363.1 dTMP kinase -
HAQ10_RS13705 2928082..2928378 - 297 WP_011257364.1 hypothetical protein -
HAQ10_RS13710 2928385..2928624 - 240 WP_011257365.1 hypothetical protein -
HAQ10_RS13715 2928621..2929295 - 675 WP_011257366.1 hypothetical protein -
HAQ10_RS13720 2929617..2930540 + 924 WP_011407409.1 arginase -
HAQ10_RS13725 2930648..2930800 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
HAQ10_RS13730 2930864..2930998 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
HAQ10_RS13735 2931242..2931451 + 210 WP_011407411.1 CsbD family protein -
HAQ10_RS13740 2931620..2932909 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
HAQ10_RS13745 2932962..2933984 + 1023 WP_011257371.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T152264 WP_011257368.1 NZ_CP050114:2930864-2930998 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T152264 NZ_CP066085:2389954-2390256 [Escherichia fergusonii]
ATGGCTCAAAAGAATAATATAAGGAGTTTTCGTGATGCCTGGCTGGCTGATTTTTTTGTCCACTCAACGCCACATAGAAA
GATTCCTGCTGAAATCCATACCACATTATCAAGAAAATTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATATTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTATTTAGATCCACACAACTACTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT152264 WP_011407410.1 NZ_CP050114:2930648-2930800 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT152264 NZ_CP066085:2390292-2390633 [Escherichia fergusonii]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAGCCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACAACTG
AAATGGCGTTTCGTCTGGCTAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCGGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACACAAGAAGAATTGGGACGGATTGAAACAGTGGCTGACTATTTGGCTCGCCGTGAAGA
GCGTGCAAAGAATGTTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References