Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 958946..960465 Replicon chromosome
Accession NZ_CP050114
Organism Xanthomonas oryzae pv. oryzae strain K3

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag HAQ10_RS04340 Protein ID WP_011259680.1
Coordinates 958946..959869 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag HAQ10_RS04345 Protein ID WP_011409027.1
Coordinates 959866..960465 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ10_RS04310 955139..955671 + 533 Protein_826 methyltransferase domain-containing protein -
HAQ10_RS04315 955688..956176 - 489 WP_011409022.1 hypothetical protein -
HAQ10_RS04320 956271..957236 + 966 Protein_828 IS1595 family transposase -
HAQ10_RS04325 957688..957930 - 243 WP_011409025.1 hypothetical protein -
HAQ10_RS04330 958363..958584 + 222 Protein_830 hypothetical protein -
HAQ10_RS04335 958657..958866 + 210 WP_042465653.1 hypothetical protein -
HAQ10_RS04340 958946..959869 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HAQ10_RS04345 959866..960465 - 600 WP_011409027.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
HAQ10_RS04355 960800..961120 + 321 WP_011409028.1 hypothetical protein -
HAQ10_RS04360 961167..961622 + 456 Protein_835 BrxE family protein -
HAQ10_RS04365 961709..962740 - 1032 WP_042465093.1 IS630 family transposase -
HAQ10_RS04370 962790..963529 + 740 Protein_837 DUF1819 family protein -
HAQ10_RS04375 963510..963728 + 219 Protein_838 DUF1788 domain-containing protein -
HAQ10_RS04385 964247..964783 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T152262 WP_011259680.1 NZ_CP050114:c959869-958946 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T152262 NZ_CP066085:c1866309-1866157 [Escherichia fergusonii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT152262 WP_011409027.1 NZ_CP050114:c960465-959866 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT152262 NZ_CP066085:1866358-1866415 [Escherichia fergusonii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References