Detailed information of TA system TA152261

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 456277..456833
• Replicon: chromosome
• Accession: NZ_CP050114
• Organism: Xanthomonas oryzae pv. oryzae strain K3

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: HAQ10_RS02090
• Protein ID: WP_027703932.1
• Coordinates: 456277..456567 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: HAQ10_RS02095
• Protein ID: WP_011408759.1
• Coordinates: 456555..456833 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAQ10_RS02045	452047..453138	+	1092	WP_011408756.1	ribonuclease D	-
HAQ10_RS02050	453235..453551	-	317	Protein_390	ATP-dependent DNA ligase	-
HAQ10_RS02055	453611..453817	-	207	Protein_391	hypothetical protein	-
HAQ10_RS02060	453833..454009	-	177	Protein_392	DUF3606 domain-containing protein	-
HAQ10_RS02065	454231..454632	+	402	WP_011259345.1	H-NS histone family protein	-
HAQ10_RS02080	455496..455675	-	180	WP_015463309.1	hypothetical protein	-
HAQ10_RS02085	455819..456016	-	198	WP_153296741.1	hypothetical protein	-
HAQ10_RS02090	456277..456567	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HAQ10_RS02095	456555..456833	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
HAQ10_RS23415	456914..457117	-	204	WP_199285669.1	hypothetical protein	-
HAQ10_RS23420	457029..457373	-	345	WP_199285675.1	hypothetical protein	-
HAQ10_RS02105	457318..457518	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
HAQ10_RS02110	458279..459463	-	1185	WP_011408397.1	IS256 family transposase	-
HAQ10_RS02115	460044..461009	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
HAQ10_RS02120	461111..461716	+	606	Protein_403	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T152261 WP_027703932.1 NZ_CP050114:c456567-456277 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T152261 NZ_CP066085:c1735819-1735355 [Escherichia fergusonii]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATACTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTACAGCGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAGCCCATTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT152261 WP_011408759.1 NZ_CP050114:c456833-456555 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT152261 NZ_CP066085:c1736154-1735819 [Escherichia fergusonii]
ATGCCCGCTAATGCTCGCTCTAACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGATTGGGAGATGAACAGGAGGATCCTACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCGACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2