152260

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4436081..4436637 Replicon chromosome
Accession NZ_CP050113
Organism Xanthomonas oryzae pv. oryzae strain K2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HAQ08_RS21030 Protein ID WP_027703932.1
Coordinates 4436347..4436637 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag HAQ08_RS21025 Protein ID WP_011408759.1
Coordinates 4436081..4436359 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ08_RS20995 4431334..4431939 - 606 Protein_3994 DNA-3-methyladenine glycosylase -
HAQ08_RS21000 4432041..4433006 - 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
HAQ08_RS21005 4433095..4433286 - 192 Protein_3996 transposase -
HAQ08_RS21010 4433451..4434635 + 1185 WP_011408397.1 IS256 family transposase -
HAQ08_RS21015 4435396..4435596 + 201 WP_027703931.1 ribbon-helix-helix protein, CopG family -
HAQ08_RS23705 4435541..4435885 + 345 WP_199285675.1 hypothetical protein -
HAQ08_RS23710 4435797..4436000 + 204 WP_199285669.1 hypothetical protein -
HAQ08_RS21025 4436081..4436359 + 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
HAQ08_RS21030 4436347..4436637 + 291 WP_027703932.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HAQ08_RS21035 4436898..4437095 + 198 WP_004541336.1 hypothetical protein -
HAQ08_RS21040 4437239..4437418 + 180 WP_015463309.1 hypothetical protein -
HAQ08_RS21055 4438282..4438683 - 402 WP_011259345.1 H-NS histone family protein -
HAQ08_RS21060 4438905..4439081 + 177 Protein_4006 DUF3606 domain-containing protein -
HAQ08_RS21065 4439097..4439303 + 207 Protein_4007 hypothetical protein -
HAQ08_RS21070 4439363..4439700 + 338 Protein_4008 ATP-dependent DNA ligase -
HAQ08_RS21075 4439776..4440867 - 1092 WP_041182166.1 ribonuclease D -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10915.48 Da        Isoelectric Point: 9.5554

>T152260 WP_027703932.1 NZ_CP050113:4436347-4436637 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T152260 NZ_CP066085:c900432-900280 [Escherichia fergusonii]
ATGCCGCAGAAATACGGATTACTTTCGTTAATAGTGATTTGTTTCACGCTTTTATTTTTCACCTGGATGATAAGAGATTC
ACTGTGTGAATTGCATATTAAACAGGAGAGTTATGAGCTGGCGGCGTTTTTAGCCTGCAAATTGAAAGAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT152260 WP_011408759.1 NZ_CP050113:4436081-4436359 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT152260 NZ_CP066085:900483-900538 [Escherichia fergusonii]
GTTGAAGCATAGAGGCAGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References