Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3945107..3946626 Replicon chromosome
Accession NZ_CP050113
Organism Xanthomonas oryzae pv. oryzae strain K2

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag HAQ08_RS18840 Protein ID WP_011259680.1
Coordinates 3945703..3946626 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag HAQ08_RS18835 Protein ID WP_011409027.1
Coordinates 3945107..3945706 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ08_RS18800 3940990..3941208 - 219 Protein_3575 DUF1788 domain-containing protein -
HAQ08_RS18805 3941189..3941928 - 740 Protein_3576 DUF1819 family protein -
HAQ08_RS18810 3941978..3943004 + 1027 WP_133264944.1 IS630 family transposase -
HAQ08_RS18815 3943147..3943945 + 799 WP_113091170.1 IS5 family transposase -
HAQ08_RS18820 3943932..3944420 - 489 WP_027703988.1 BrxE family protein -
HAQ08_RS18825 3944452..3944772 - 321 WP_011259682.1 hypothetical protein -
HAQ08_RS18835 3945107..3945706 + 600 WP_011409027.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
HAQ08_RS18840 3945703..3946626 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HAQ08_RS18845 3946706..3946954 - 249 WP_033013473.1 hypothetical protein -
HAQ08_RS18850 3946988..3947209 - 222 Protein_3584 hypothetical protein -
HAQ08_RS18855 3947642..3947884 + 243 WP_011259679.1 hypothetical protein -
HAQ08_RS18860 3948309..3948818 + 510 WP_011259678.1 hypothetical protein -
HAQ08_RS18865 3948835..3949367 - 533 Protein_3587 methyltransferase domain-containing protein -
HAQ08_RS18870 3949387..3950763 - 1377 Protein_3588 IS5 family transposase -
HAQ08_RS18875 3950875..3951027 - 153 Protein_3589 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T152259 WP_011259680.1 NZ_CP050113:3945703-3946626 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T152259 NZ_CP066085:c871039-870932 [Escherichia fergusonii]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT152259 WP_011409027.1 NZ_CP050113:3945107-3945706 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT152259 NZ_CP066085:871087-871153 [Escherichia fergusonii]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References