Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1930662..1931012 Replicon chromosome
Accession NZ_CP050113
Organism Xanthomonas oryzae pv. oryzae strain K2

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag HAQ08_RS09260 Protein ID WP_011257368.1
Coordinates 1930662..1930796 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag HAQ08_RS09265 Protein ID WP_011407410.1
Coordinates 1930860..1931012 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAQ08_RS09245 1927676..1928698 - 1023 WP_011257371.1 MBL fold metallo-hydrolase -
HAQ08_RS09250 1928751..1930040 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
HAQ08_RS09255 1930209..1930418 - 210 WP_011407411.1 CsbD family protein -
HAQ08_RS09260 1930662..1930796 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
HAQ08_RS09265 1930860..1931012 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
HAQ08_RS09270 1931120..1932043 - 924 WP_011407409.1 arginase -
HAQ08_RS09275 1932365..1933039 + 675 WP_011257366.1 hypothetical protein -
HAQ08_RS09280 1933036..1933275 + 240 WP_011257365.1 hypothetical protein -
HAQ08_RS09285 1933282..1933578 + 297 WP_011257364.1 hypothetical protein -
HAQ08_RS09290 1934058..1934741 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T152257 WP_011257368.1 NZ_CP050113:c1930796-1930662 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T152257 NZ_CP066085:418286-418627 [Escherichia fergusonii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGTCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACTGCCCAACCACCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCACTGCGCCAGGTATGCAAATTGTCGGCGCGTAAACAAAAGCAGGTGCAGGATTTTATTGGGGTAATTGC
GGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT152257 WP_011407410.1 NZ_CP050113:c1931012-1930860 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT152257 NZ_CP066085:c418291-418215 [Escherichia fergusonii]
AGTCATAACTGCTATTCTCCTGAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References