Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 695552..696087 Replicon plasmid pRL22b6
Accession NZ_CP050092
Organism Rhizobium leguminosarum bv. trifolii strain 22B

Toxin (Protein)


Gene name relE Uniprot ID A0A8G2MTM4
Locus tag HA462_RS28720 Protein ID WP_028742965.1
Coordinates 695812..696087 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8G2J5T9
Locus tag HA462_RS28715 Protein ID WP_028742964.1
Coordinates 695552..695812 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HA462_RS28695 691381..692394 - 1014 WP_130804410.1 ABC transporter substrate-binding protein -
HA462_RS28700 692739..693749 - 1011 WP_130784761.1 helix-turn-helix domain-containing protein -
HA462_RS28705 693746..694324 - 579 WP_183637503.1 isochorismatase family protein -
HA462_RS28710 694518..695267 - 750 WP_011649428.1 FadR family transcriptional regulator -
HA462_RS28715 695552..695812 + 261 WP_028742964.1 ribbon-helix-helix domain-containing protein Antitoxin
HA462_RS28720 695812..696087 + 276 WP_028742965.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HA462_RS28725 696094..697101 - 1008 WP_130804406.1 LacI family transcriptional regulator -
HA462_RS28730 697309..698631 + 1323 WP_166478754.1 alpha-L-fucosidase -
HA462_RS28735 698682..699905 + 1224 WP_131600731.1 sugar ABC transporter substrate-binding protein -
HA462_RS28740 699988..700962 + 975 WP_204333697.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..826637 826637


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10826.48 Da        Isoelectric Point: 9.9288

>T152243 WP_028742965.1 NZ_CP050092:695812-696087 [Rhizobium leguminosarum bv. trifolii]
MELKWTSKAVSDVARLYDFLAPVDRLAAARTVQALTKAPARLLDQPRLGERLEEFDPREVRRILVGRYELRYEIQQSTIY
VLRLWHTREDR

Download         Length: 276 bp

>T152243 NZ_CP066071:c4073698-4073288 [Providencia stuartii]
GTGGTCCTGTGGAAATCTAATCTCTCCATTTCATGGAAAACTCAGCTTTTTTCAACCTGTGCTCATGGGGTAGTCGGCTT
TATTCTATTGGTCGCACCATGGGCGCCAGGGAATTCAATGGTGTGGTTGCCGCTGTTAGTGATTGTGATTGCTAGCTGGG
CAAAAAGCCAAAAAAGCATCAGCAAAATCAAAGGGACTGCGGTGCTGGTTAATGGCAATAAAGTCCAATGGAAAAAGAAT
GAGTGGAGTATCGTTAAGCAACCTTGGTGTAGCCGTGTGGGGGTATTATTGACACTCAGTGCCTTACAAGGTAAGCCACA
GAAGATCCGTTTATGGGTTGCAAAAGATGCCTTATCAGAAGAGAGCTGGCGTAATTTAAACCAACTATTACTGCAATATC
CTGATATTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9630.82 Da        Isoelectric Point: 4.6005

>AT152243 WP_028742964.1 NZ_CP050092:695552-695812 [Rhizobium leguminosarum bv. trifolii]
METKVLTAHVPLSLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDDGNVVDHQSVQAWADSLDGDA
PISLPR

Download         Length: 261 bp

>AT152243 NZ_CP066071:c4073945-4073679 [Providencia stuartii]
ATGGATATAGAGAATAAAGCAAGAATTCATTGGGCTTGCCGTCGTGGTATGCGTGAGTTGGATATTTCCATCATGCCATT
CTTTGAATATGAATATGAAGGACTCTCTGACAAGGACAAACGTACTTTTGTTCGTTTACTTGAGTGTGCAGACCCTGATC
TGTTTAACTGGTTAATGAATCATGGGCGCCCAGACGACGATGAGTTGTTTGGTATGGTTAAATTGATTCAGGAAAGAAAT
AAAAATCGTGGTCCTGTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References