Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 467143..467675 Replicon plasmid pRL31b3
Accession NZ_CP050083
Organism Rhizobium leguminosarum bv. trifolii strain 31B

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HA464_RS34315 Protein ID WP_075223727.1
Coordinates 467143..467436 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HA464_RS34320 Protein ID WP_178385434.1
Coordinates 467433..467675 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HA464_RS34295 462875..463918 - 1044 WP_018070765.1 ABC transporter permease -
HA464_RS34300 463918..465435 - 1518 WP_018070764.1 sugar ABC transporter ATP-binding protein -
HA464_RS34305 465432..466430 - 999 WP_018070763.1 LacI family transcriptional regulator -
HA464_RS34310 466629..467069 + 441 WP_075223726.1 fucose dissimilation pathway protein FucU -
HA464_RS34315 467143..467436 - 294 WP_075223727.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HA464_RS34320 467433..467675 - 243 WP_178385434.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HA464_RS34325 467841..468743 - 903 WP_163856570.1 MBL fold metallo-hydrolase -
HA464_RS34330 468846..469478 - 633 WP_130687235.1 DsbA family protein -
HA464_RS34335 469593..470477 + 885 WP_075223731.1 LysR family transcriptional regulator -
HA464_RS34340 470638..470916 + 279 WP_018070756.1 acylphosphatase -
HA464_RS34345 471059..471712 + 654 WP_075223732.1 Rieske (2Fe-2S) protein -
HA464_RS34350 471709..472554 + 846 WP_075223733.1 aromatic ring-hydroxylating dioxygenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..644077 644077


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11263.77 Da        Isoelectric Point: 4.9230

>T152231 WP_075223727.1 NZ_CP050083:c467436-467143 [Rhizobium leguminosarum bv. trifolii]
MSFKLSAEAEEDIIAIAEQGVRMFGAGQAKRYHDELFALFDLIAVNPRFARERDEIDPPVRIHPFKAHLIVYRIEDDETI
FVVRIRHAHEDWASDSI

Download         Length: 294 bp

>T152231 NZ_CP066060:2332057-2332434 [Actinomyces oris]
GTGATCCTTGTCGACACCTCGGTATGGATCGATCACTTCCACCACTCGGACCCAGTACTCGTCAGCCTGCTGCACGAGGA
CGAGATCGGATCCCATCCACTCGTGGCGGAGGAGCTGGCGATGGGGTCACTCAGGGCCAGAGATGACGTTCTCAAGCACT
TAGCGCACCTCCGCCAGTTCCCGGTCCTCTCACATGACGAGCTACTGACTCTGGTCGCAGCCCCTGCGCTGTGGGGTCGA
GGACTCAGCCCAGTCGATGCGCACCTGCTCGGCTCCGTCACGCTGGTCCCTGGCGCCCGCCTGTGGACACGCGACAAGCG
ATTGCTCCGCGCTGCCGAAGAGCGCGGAGTCTCCTTCACCGAAGGAACCGCCGGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8925.04 Da        Isoelectric Point: 8.5615

>AT152231 WP_178385434.1 NZ_CP050083:c467675-467433 [Rhizobium leguminosarum bv. trifolii]
MATMNVSLPGPMKDWVEDQARTGRYSNASDYVRDLIRRDQTRNDKIAAMQSFVEAGLQSGVGIRSKDELFAEAMARANKS

Download         Length: 243 bp

>AT152231 NZ_CP066060:2331863-2332060 [Actinomyces oris]
GTGCGAACCACCGTGACACTCAGTGATGACCTCATTGCCAACGCGCAAGAGCTCACAGGCATCACTGAGCGCACCGAGCT
GCTGCGGGCCGGCCTGGAGACCCTGGTCAGAGTGGAGAGCGCACGTCGCCTTGCGGCTCTCGGCGGCTCTGATCGGACGG
CGAGCGCCGCTCCACGACGTCGGAGCGCCAGCCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References