Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 5356753..5357291 Replicon chromosome
Accession NZ_CP050066
Organism Bradyrhizobium symbiodeficiens strain 101S1MB

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag HAV00_RS25415 Protein ID WP_094977521.1
Coordinates 5357025..5357291 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HAV00_RS25410 Protein ID WP_094977520.1
Coordinates 5356753..5357019 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAV00_RS25385 5352826..5353155 - 330 WP_166470090.1 hypothetical protein -
HAV00_RS25390 5353339..5354577 - 1239 WP_166469111.1 acyltransferase -
HAV00_RS25395 5354751..5355203 - 453 WP_166469112.1 hypothetical protein -
HAV00_RS25400 5355246..5355932 - 687 WP_166470091.1 hypothetical protein -
HAV00_RS25405 5356347..5356514 - 168 WP_008139339.1 50S ribosomal protein L33 -
HAV00_RS25410 5356753..5357019 + 267 WP_094977520.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HAV00_RS25415 5357025..5357291 + 267 WP_094977521.1 Txe/YoeB family addiction module toxin Toxin
HAV00_RS25420 5357295..5358623 - 1329 WP_166469113.1 LLM class flavin-dependent oxidoreductase -
HAV00_RS25425 5358851..5359600 - 750 WP_094977523.1 NUDIX domain-containing protein -
HAV00_RS25430 5359631..5360071 - 441 WP_094977524.1 DUF983 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10662.24 Da        Isoelectric Point: 8.9066

>T152172 WP_094977521.1 NZ_CP050066:5357025-5357291 [Bradyrhizobium symbiodeficiens]
MLIAWTEIAWQDYLRWQQEDEKILSAINDLIKDIKRDPFKGIGKPEPLKHDLRGWWSRRITGEHRLVYRLQGKDDAQQLV
IAQCRYHY

Download         Length: 267 bp

>T152172 NZ_CP066019:c2190530-2190120 [Cupriavidus necator]
ATGACGCGCTACATGCTCGACACCAATATCGTGAGCCTTCTGTTGCGGGCACATCCGGCAGTCGTGGCACGCGTGACGGC
AGCGCCGATGGTGGCGCTGTGCCTGTCAGCCATCACCGGTGCGGAACTGATGTACGGGCTGGCCAAGCGTCCCGGCGCAG
CGCGCCTCGCGCGCGCGGTCGACGAGTTGCTGCGCAGGGTCGAGGTATTGCCCTGGACCCCTTCAGTGATGGCCGGCTAT
GGTGAAACCCGCGCTGCGCTGGAATCCCAAGGACAGCCGGTGGGGGCACTGAACCTGCTGATCGCCGCGCACGCGCTGGA
GACTGGCGCGGTGCTGGTGACCAATGACCAGGCATTCCGGCGCGTCCCTGGCCTGGTGGTGGAGGACTGGACGGTTCCGA
CCGGAAATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9664.97 Da        Isoelectric Point: 4.8254

>AT152172 WP_094977520.1 NZ_CP050066:5356753-5357019 [Bradyrhizobium symbiodeficiens]
MAHVSYTELRGNLAAYMDQVCDDRAPLVVTRQNARSVVMLSEEEYEGLVETVHLLKSPANAARLLRSIKEADEGKLVAHE
LIEPGSTG

Download         Length: 267 bp

>AT152172 NZ_CP066019:c2190778-2190527 [Cupriavidus necator]
GTGAGCACCACTGCCAAGATCTTCACCACCGGCCGCAGCCAGGCGGTACGGCTGCCGCAGGAATTCCGCTTCGCCGAGCG
CGAGGTATATATTCGCCGTGACCCGTCCACCGGTGACGTGATCCTGTCGCGCCGGCCGGAGAGTTGGGACGGCTTTTTGG
CTGCCATCAAGGACAGCGCCGTGCCGGAAGACTTTATGGCCGACCGCGCGCAGGGCGAGCAAGCCAGGGATCCGCTGGCG
GGTCTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References