152169

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 166375..167015 Replicon chromosome
Accession NZ_CP050066
Organism Bradyrhizobium symbiodeficiens strain 101S1MB

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HAV00_RS00735 Protein ID WP_166466408.1
Coordinates 166375..166665 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HAV00_RS00740 Protein ID WP_166466409.1
Coordinates 166665..167015 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAV00_RS00710 161567..162205 - 639 WP_094975195.1 DUF1109 domain-containing protein -
HAV00_RS00715 162208..162753 - 546 WP_094975196.1 sigma-70 family RNA polymerase sigma factor -
HAV00_RS00720 163045..163731 + 687 WP_166466406.1 hypothetical protein -
HAV00_RS00725 163882..164661 + 780 WP_166466407.1 enoyl-CoA hydratase -
HAV00_RS00730 164881..166278 + 1398 WP_162308455.1 TolC family outer membrane protein -
HAV00_RS00735 166375..166665 + 291 WP_166466408.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HAV00_RS00740 166665..167015 + 351 WP_166466409.1 putative addiction module antidote protein Antitoxin
HAV00_RS00745 167100..167657 + 558 WP_166466410.1 hypothetical protein -
HAV00_RS00750 167710..168669 + 960 WP_166466411.1 amidohydrolase family protein -
HAV00_RS00755 168673..171789 - 3117 WP_094975201.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-92)

Antitoxin

Uncharacterized protein HI1420

(12-105)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11219.86 Da        Isoelectric Point: 10.4999

>T152169 WP_166466408.1 NZ_CP050066:166375-166665 [Bradyrhizobium symbiodeficiens]
MIEVRQTERFSEWLNRLEDASAVARITARIRRMEMGNPGDSKGVGRNLREMRIDYGPGYRIYYVQRGRQITILLCGGDKR
TQRQDIKLAQQLAETF

Download         Length: 291 bp

>T152169 NZ_CP066019:725286-725714 [Cupriavidus necator]
ATGATCGTCCTGGATACCAACGTTATTTCCGAGGCCATGAAGCCGGAACCGGCCGATGCCGTGCGCGGCTGGCTCAACGA
CCAGGCCGCCGAGACCTTGTACCTGTCCAGTGTGACGCTGGCCGAACTGCTGTTCGGCATCGGCGCGCTGCCGGCGGACA
GGCGCCGCGCCATGCTGGCCGCTGCGCTGGACGGCCTGGTGACGCTGTTCGAAGGGCGCATCTTGCCGTTCGACACGAAT
GCGGCCCGGCACTATGCGGAACTCGCCGTTGCCGCCAGAAGCCGTGGCCGCGGCCTTCCCGCGCCGGATGGCTACATCGC
CGCGATTGCCGCGGCCAACGGCATGATGGTCGCGACACGGGACGTGTCGCCCTTTGAAGCGGCCGGGCTGCAGGTGCTCA
ATCCGTGGCAGGCGCCGCCTCCGTCGTGA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12374.21 Da        Isoelectric Point: 10.9396

>AT152169 WP_166466409.1 NZ_CP050066:166665-167015 [Bradyrhizobium symbiodeficiens]
MPKAVKTTVKATSRTTRFDAADYLNTEERQAAYIAAALETGDADFVRDALGLVARARGMSAIAKKAGLNRESLYKALGET
GNPEFGTVMRIVAALGLTLSAQPTTSGRMPKRRRAA

Download         Length: 351 bp

>AT152169 NZ_CP066019:725035-725289 [Cupriavidus necator]
ATGCCGATCCTGACCGTTAGAAATGTGCCCGACGACGTGCATCGTGCGCTGCGGGTCCGTGCCGCCCGGAACGGACGCAG
TACCGAGGCTGAGGTGCGTCAGATCCTGGCCAGCGCGGTGATGCCGCAGAAGCGCGTGCGCCTGGGCGATGCGCTGGCGA
TGCTTGGCCGCGAGATCGGCCTGTCGAATGCGGACGTTGAAGCGATCGGGCAGGGCAAGGACAAGGCAGCGGCCGAGCCG
GTGAGGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References