Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3082296..3083131 Replicon chromosome
Accession NZ_CP050047
Organism Escherichia coli strain 90-1

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag G9P52_RS14805 Protein ID WP_001565141.1
Coordinates 3082296..3082673 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag G9P52_RS14810 Protein ID WP_001565140.1
Coordinates 3082763..3083131 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9P52_RS14775 3077662..3078585 - 924 WP_000535960.1 carboxylate/amino acid/amine transporter -
G9P52_RS14780 3078696..3079880 - 1185 WP_001172876.1 sugar efflux transporter -
G9P52_RS14785 3080309..3080437 - 129 Protein_2877 virulence RhuM family protein -
G9P52_RS14790 3080675..3081517 - 843 WP_001565143.1 DUF4942 domain-containing protein -
G9P52_RS14795 3081602..3081799 - 198 WP_000839256.1 DUF957 domain-containing protein -
G9P52_RS14800 3081811..3082299 - 489 WP_001565142.1 hypothetical protein -
G9P52_RS14805 3082296..3082673 - 378 WP_001565141.1 TA system toxin CbtA family protein Toxin
G9P52_RS14810 3082763..3083131 - 369 WP_001565140.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
G9P52_RS14815 3083206..3083427 - 222 WP_000692303.1 DUF987 domain-containing protein -
G9P52_RS14820 3083496..3083972 - 477 WP_188027846.1 RadC family protein -
G9P52_RS14825 3083988..3084473 - 486 WP_188027847.1 antirestriction protein -
G9P52_RS14830 3084565..3085383 - 819 WP_188027848.1 DUF945 domain-containing protein -
G9P52_RS14835 3085474..3085707 - 234 WP_021543798.1 DUF905 family protein -
G9P52_RS14840 3085786..3086241 - 456 WP_021543797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(19-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14246.27 Da        Isoelectric Point: 7.2920

>T152139 WP_001565141.1 NZ_CP050047:c3082673-3082296 [Escherichia coli]
MKTLPDTHVREASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SICPRSQLINSIDILRARRATGLMTRDNYRMVNNITQGKHPEAQQ

Download         Length: 378 bp

>T152139 NZ_CP065997:2266208-2267470 [Achromobacter deleyi]
ATGAGCGTCGACGCGCTCGATCTTTACCAGGCGGATCGCAAGGTCGGCCGCCTGTTCGACGAACGGCCCCTGCGTTTCGT
CTATGACGATGCCTGGCTGGGATGGCCTGCGGCGCATGCCATCGCGCCGGACATCCCGCTGCGCGACGGCGACCATGCCG
GCGAGGCGGTGCATGCCTTCTTCGAAAACCTGCTGCCCGAAGGGCGCCTGCGCCGATTCCTGCAAGTCAGCCGCCACGCC
ACGACCGTCTTCGGCCTGCTGCGCAGCGTCGGGGGCGACACGGCCAGCGGCCTGACGATATGGCCGCAAGGCGAACGGCC
GGCGCCGCCGCGCTATCGCGCCACGACCTGGGGCGAGATCGCCGCGCGTCTGCAGGATCCGGCACAGCCAGCCCTGGTTG
CCGAGAACGCCGACGGTGCGCGCATTTCACTGGCGGGCGCGCAGGACAAGCTGCTGCTGATGGTCATGCCGGACGGCGCG
CCGGCCTGGCCCGAGGGCGCCGCGCCCTCCATGCATATCCTCAAGCCGGACATCCGCGGGTTTGATGGCGTCTGGTCATC
GGCGCTCAATGAAACCCTGGTGATGCAATTGGCGGCGCGCCTGGGGCTGGGCGTGGCCGAGGCGGGCCTGCAACCGGATA
CCCGGGCGTGCCTGGTCACCCGCTACGATCGCGCGCCGGACGGCGCGGCAGGCCTGCGGCGCCTGCATCAGCTCGATCTG
TGCCAGTTGGCAGGCAAGCCCTCGGATGTGAAATACGAAGCCGATGGCGGGCCGTCGCTGGCGCAGTGCCGCGAACTGCT
CAGGGGCATGGGCGTCAACGCGGCGGACCTCAAGCGCTTCCTGCAGTGGGTGCTTTTCAACCTTTGCGTCGGCAATAACG
ACAGCCATGCCAAGAACCTGTCCGTGCTGCAAACGCCGGATGGCCAGTACCGCCTGGCGCCGTTCTATGACCTGATGTGT
ACCGCGCTGTACCCCGGCCTGGCCTGCAATTTCGCGTTCGCCGTGGGCGGCGAGTCCAGGCCGGGCCACATTGGCCGCGG
GCACCTGGATGCCATGGCGCGGGAACTGGGCTTCAGCCCCCGCTACGTGGCTGGCGTGGCGCAGGCGCTGGTGACGGAAC
TGCCGTCTGCGCTGGAAACGGTGCAGGCCGACCTGGCGCGGCAGGCTACGGCGGGCACGGAAAGCACGCTGCTCGAGCGT
CTGGGCCAATGGATCCGGGCCAACACTCGCAAGCTCGCCAAACGCTGGGAATTGCCGGGCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13604.41 Da        Isoelectric Point: 6.7389

>AT152139 WP_001565140.1 NZ_CP050047:c3083131-3082763 [Escherichia coli]
VSDTLPGTTHPDDNHDRLWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSNADAYHLDQAFALLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPETKK

Download         Length: 369 bp

>AT152139 NZ_CP065997:2265954-2266211 [Achromobacter deleyi]
ATGCCCTCGCCATCTTCCACTGATGGAGCCTCCATCGCCATCCACACCTCCGCCGAACTCGGTGAATTGGTGAAGGACGT
ACGCCGCGCGCAAGGGCTGCTGCAAACAGACCTGGCCGGCCTGTCCGGCACCGGCAATCGTTTCGTGGTGGACCTGGAGC
GGGGCAAGCCAACGCTGCAGTTGCAGAAGGTGCTCGACATGCTGGACCTGCTGGGCCTGGAAGTGCGGGTCGGTCCCAAG
CGCGTGGGCCGGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References