Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2164518..2165082 Replicon chromosome
Accession NZ_CP049990
Organism Pusillimonas sp. DMV24BSW_D

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G9Q38_RS10525 Protein ID WP_205962371.1
Coordinates 2164807..2165082 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G9Q38_RS10520 Protein ID WP_137430352.1
Coordinates 2164518..2164769 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9Q38_RS10495 2159789..2160568 - 780 WP_166130717.1 NRDE family protein -
G9Q38_RS10500 2160576..2161409 - 834 WP_166130719.1 D-alanyl-D-alanine endopeptidase -
G9Q38_RS10505 2161541..2162056 + 516 WP_166130722.1 cupin domain-containing protein -
G9Q38_RS10510 2162053..2162595 - 543 WP_166130725.1 DUF924 domain-containing protein -
G9Q38_RS10515 2162780..2164273 + 1494 WP_166130728.1 amidase -
G9Q38_RS10520 2164518..2164769 + 252 WP_137430352.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G9Q38_RS10525 2164807..2165082 + 276 WP_205962371.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G9Q38_RS10530 2165206..2166240 - 1035 WP_166130733.1 hypothetical protein -
G9Q38_RS10535 2166733..2167320 + 588 WP_166130736.1 inovirus Gp2 family protein -
G9Q38_RS10540 2167419..2167673 + 255 WP_166130739.1 AlpA family transcriptional regulator -
G9Q38_RS10545 2167911..2168804 - 894 WP_166130741.1 hypothetical protein -
G9Q38_RS10550 2168888..2169388 - 501 WP_166130744.1 DNA repair protein RadC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-76)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-78)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10325.21 Da        Isoelectric Point: 8.8879

>T151984 WP_205962371.1 NZ_CP049990:2164807-2165082 [Pusillimonas sp. DMV24BSW_D]
MPEALAEWNALDGSVKAVLKKLLLKRLEQPRTPGAELRGDLRDCYKIKLLKQGYRLVYLVEDDVLVVLVLAVSKREDMEV
YRAAVDRLLSG

Download         Length: 276 bp

>T151984 NZ_CP065866:1590523-1591392 [Pseudomonas aeruginosa]
ATGAACATGGCGCAGACCCACACCCCCGTCCCGAACCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGTTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGTGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCTTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCTCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGTCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9283.60 Da        Isoelectric Point: 4.7672

>AT151984 WP_137430352.1 NZ_CP049990:2164518-2164769 [Pusillimonas sp. DMV24BSW_D]
MDTIYADYSVSMSEFKKNPAQVLRTAGEKPVAVLNHNRPAFYMITPKLFEALVEELSDRDLAELARQRLANKGAAVEVDI
DSL

Download         Length: 252 bp

>AT151984 NZ_CP065866:1591385-1592218 [Pseudomonas aeruginosa]
ATGGATAAGTCAGACGATTCGCAAGACAAGTACATCGTGCCTGGCCTCGAACGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGGACCGTACCCTGACGGCGCCGGAGTTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAGGCCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGTTGCGCCTGGGCTTC
GAGTACCTGGCCTCGCTGGAGCTGACCGAACTCGGCCAGCCGCTGCTGAACCGCCTGTGCGACGAGATCCGCTACCCCTG
CAACCTGGTGGTGCGCGACGGCCGTTCGATCGTCTACGTGGCCAAGGTCTCGCCGTCCACCCCGCTGAGCAGCTCGGTGA
ACGTTGGGACCCGGTTGCCGGCCCACGCCACGGTGCTCGGCCGCATCCTGCTGCAGGACCTGAGCCTGGGCGAGCTGCGC
GAGCTGTACCCGGAGGAGCAGCTGGAGCAGTTCTCGCCGAACACCCCGCGCAGCGTGCTGGAACTCTTCGACATGGTCCA
GGGCGACCGCCAGCGTGGCTTCGTCCAGGGCGAGGGGTTCTTCGAGGCGAGCATCTCCACCGTCGCGGCACCGGTACGTG
ATCACAGCGGTCGCGTCATCGCGGCGATGGGGGCGACCATCGCCGCAGGGCATATCGACCCGGAACGCATCGAGGGACTG
GTCAGCCGGGTGCGCAGCAGCGCCGACGAGCTGTCGTACCTGCTCGACTACCGCGCCGACGGCCAGGACAACGTCACCCC
GATCTTCCGGAGTCGCTCGCATGAAACCGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References