151982

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 531439..531989 Replicon chromosome
Accession NZ_CP049990
Organism Pusillimonas sp. DMV24BSW_D

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G9Q38_RS02505 Protein ID WP_166127503.1
Coordinates 531699..531989 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G9Q38_RS02500 Protein ID WP_166132289.1
Coordinates 531439..531711 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9Q38_RS02480 526588..528273 - 1686 WP_166127498.1 AMP-binding protein -
G9Q38_RS02485 528294..529160 - 867 WP_166127500.1 VOC family protein -
G9Q38_RS02490 529172..530419 - 1248 WP_119515860.1 alpha/beta hydrolase -
G9Q38_RS02495 530605..531321 + 717 WP_114419172.1 TetR/AcrR family transcriptional regulator -
G9Q38_RS02500 531439..531711 + 273 WP_166132289.1 CopG family ribbon-helix-helix protein Antitoxin
G9Q38_RS02505 531699..531989 + 291 WP_166127503.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G9Q38_RS02510 531994..532971 - 978 WP_166127506.1 asparaginase -
G9Q38_RS02515 532974..533684 - 711 WP_166127509.1 ABC transporter ATP-binding protein -
G9Q38_RS02520 533677..534450 - 774 WP_166132290.1 ABC transporter ATP-binding protein -
G9Q38_RS02525 534447..535706 - 1260 WP_166127512.1 penicillin-binding protein activator -
G9Q38_RS02530 535752..536702 - 951 WP_119441837.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10644.18 Da        Isoelectric Point: 8.9347

>T151982 WP_166127503.1 NZ_CP049990:531699-531989 [Pusillimonas sp. DMV24BSW_D]
VSRLIWSPAALADTQRLYRFLAPKNKAAAQRAITAIRNGVKMLAAQPEAGCPLDDLDPNFREWIIDFGGSGYVVLYHFNG
HESVILAVRNQKEAGY

Download         Length: 291 bp

>T151982 NZ_CP065865:c6070707-6070429 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTAGGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10612.75 Da        Isoelectric Point: 5.1979

>AT151982 WP_166132289.1 NZ_CP049990:531439-531711 [Pusillimonas sp. DMV24BSW_D]
MATTVKLDDDLKDRIQNLAKARHRSAHWIMREAIRHYVDQEEKREAFKQDALRAWQNYQEDGQHLTSEEADAWLEKLEAG
LDAEPPKCHD

Download         Length: 273 bp

>AT151982 NZ_CP065865:c6070417-6070112 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTTGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References