Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4274836..4275605 Replicon chromosome
Accession NZ_CP049989
Organism Hydrogenophaga sp. BA0156

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag G9Q37_RS20340 Protein ID WP_205710795.1
Coordinates 4275117..4275605 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag G9Q37_RS20335 Protein ID WP_166230214.1
Coordinates 4274836..4275105 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9Q37_RS20305 4270705..4271046 + 342 WP_166230202.1 flagellar transcriptional regulator FlhD -
G9Q37_RS20310 4271079..4271618 + 540 WP_166230204.1 flagellar transcriptional regulator FlhC -
G9Q37_RS20315 4271774..4272637 + 864 WP_166230206.1 flagellar motor stator protein MotA -
G9Q37_RS20320 4272655..4273695 + 1041 WP_166230208.1 flagellar motor protein MotB -
G9Q37_RS20325 4273738..4274124 + 387 WP_166230210.1 chemotaxis response regulator CheY -
G9Q37_RS20330 4274139..4274756 + 618 WP_166230212.1 protein phosphatase CheZ -
G9Q37_RS20335 4274836..4275105 + 270 WP_166230214.1 DUF1778 domain-containing protein Antitoxin
G9Q37_RS20340 4275117..4275605 + 489 WP_205710795.1 GNAT family N-acetyltransferase Toxin
G9Q37_RS20345 4275734..4276888 + 1155 WP_166230217.1 flagellar biosynthesis protein FlhB -
G9Q37_RS20350 4276885..4278960 + 2076 WP_166230219.1 flagellar biosynthesis protein FlhA -
G9Q37_RS20355 4279002..4280489 + 1488 WP_166230221.1 flagellar biosynthesis protein FlhF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-143)

Antitoxin

Vibrio phage ICP1, Orf50

(4-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17112.74 Da        Isoelectric Point: 9.2122

>T151980 WP_205710795.1 NZ_CP049989:4275117-4275605 [Hydrogenophaga sp. BA0156]
MRAPEPLTAEHDSSAFVCKHPALTEWLQKRALSNQASGASSTYVVCTEDRAVVGYYALAPGAVAHAVATGPVRRNMPSPV
PVFVLGRLGVRADWGGRGIGAGLLRDALLRSAQAARIVGGRALLCHAIDDEARSFYLRHGFQPSGLEPMTLMVGLQGLGP
LV

Download         Length: 489 bp

>T151980 NZ_CP049989:4275117-4275605 [Hydrogenophaga sp. BA0156]
CTGCGCGCACCCGAGCCCCTCACCGCCGAGCACGACAGCTCGGCCTTCGTGTGCAAGCACCCGGCGCTGACCGAATGGCT
GCAAAAGCGCGCCCTGAGCAACCAGGCCAGCGGGGCATCTAGCACCTACGTGGTGTGCACGGAGGACCGGGCCGTGGTGG
GCTATTACGCGCTGGCGCCCGGGGCCGTCGCCCACGCCGTGGCCACCGGTCCGGTGCGGCGCAACATGCCCAGCCCGGTG
CCGGTGTTCGTGCTGGGCCGGCTGGGCGTTCGGGCCGACTGGGGCGGTCGCGGCATCGGCGCGGGGCTGCTGCGGGACGC
CTTGCTGCGCAGCGCGCAGGCCGCGCGCATCGTCGGCGGGCGCGCCCTGCTGTGTCACGCCATCGACGATGAAGCCCGCT
CGTTCTATCTGCGGCACGGCTTCCAGCCTTCGGGCCTCGAACCCATGACCCTCATGGTCGGGCTGCAGGGCCTCGGTCCG
CTGGTCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9852.22 Da        Isoelectric Point: 5.0338

>AT151980 WP_166230214.1 NZ_CP049989:4274836-4275105 [Hydrogenophaga sp. BA0156]
MQAAATTINVRAPAEVRDLIDRAAQAQGKTRTDFMLEASVEAARRVLLDQVFFQADEAQMKAFQAVMEQPVEYNAAVRAL
LSRQAPWSA

Download         Length: 270 bp

>AT151980 NZ_CP049989:4274836-4275105 [Hydrogenophaga sp. BA0156]
ATGCAAGCCGCCGCCACCACCATCAATGTCCGTGCACCCGCCGAGGTGCGCGACCTCATCGACCGCGCCGCCCAGGCCCA
GGGCAAGACACGCACCGACTTCATGCTCGAGGCGTCTGTCGAGGCGGCCCGCCGCGTGCTGCTCGACCAGGTGTTTTTCC
AGGCCGACGAGGCCCAGATGAAAGCCTTCCAGGCGGTGATGGAGCAGCCCGTCGAATACAACGCGGCCGTTCGCGCCCTG
CTGTCGCGCCAAGCCCCGTGGTCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References