Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 4419292..4420875 Replicon chromosome
Accession NZ_CP049956
Organism Stenotrophomonas maltophilia strain NCTC10498

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag G6Z48_RS20780 Protein ID WP_049419249.1
Coordinates 4419292..4420614 (-) Length 441 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag G6Z48_RS20785 Protein ID WP_005407534.1
Coordinates 4420618..4420875 (-) Length 86 a.a.

Genomic Context

G6Z48_RS20775G6Z48_RS20795G6Z48_RS20765G6Z48_RS20770G6Z48_RS20780G6Z48_RS20785G6Z48_RS20790
Location: 4418677..4419291 (615 bp)
Type: Others
Protein ID: WP_012478716.1
Location: 4424895..4425530 (636 bp)
Type: Others
Protein ID: WP_005407536.1
Location: 4414693..4416327 (1635 bp)
Type: Others
Protein ID: WP_005407530.1
Location: 4416358..4417989 (1632 bp)
Type: Others
Protein ID: WP_012478715.1
Location: 4419292..4420614 (1323 bp)
Type: Toxin
Protein ID: WP_049419249.1
Location: 4420618..4420875 (258 bp)
Type: Antitoxin
Protein ID: WP_005407534.1
Location: 4421037..4424723 (3687 bp)
Type: Others
Protein ID: WP_100443437.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G6Z48_RS207654414693..4416327-1635WP_005407530.1TldD/PmbA family protein-
G6Z48_RS207704416358..4417989-1632WP_012478715.1TldD/PmbA family protein-
G6Z48_RS207754418677..4419291+615WP_012478716.1DUF938 domain-containing protein-
G6Z48_RS207804419292..4420614-1323WP_049419249.1type II toxin-antitoxin system HipA family toxinToxin
G6Z48_RS207854420618..4420875-258WP_005407534.1helix-turn-helix transcriptional regulatorAntitoxin
G6Z48_RS207904421037..4424723-3687WP_100443437.1indolepyruvate ferredoxin oxidoreductase family protein-
G6Z48_RS207954424895..4425530+636WP_005407536.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-70)


Sequences

Toxin        


Download         Length: 441 a.a.        Molecular weight: 49049.98 Da        Isoelectric Point: 6.9606

>T151878 WP_049419249.1 NZ_CP049956:c4420614-4419292 [Stenotrophomonas maltophilia]
MGTLQVWMNGVEVALWDDVRNGSPRLSYVSQWISSPQSRPLSLSLPLLPDGESHRGNVVNDYFDNLLPDNVAIRNRIRDR
FATRGSDTFDLLEAIGRDCVGAVQLLPPAHPPEDIQQITCEVLDEAGVATILRQVTTGNLPGAPSRDDAFRISIAGAQEK
TGLLLHAGKWCIPTGNTPSTHIFKLPLGIVGNMRADMHQSVENEWLCMHLLSAFDIPVAETQMGRFNDQRALIVERFDRR
LSADRRWWLRLPQEDMCQVFGLPAARKYESDGGPGIVPIMDLLRQSEHPEDRAIFFKTQILFWMLAATDGHAKNFSVHLE
AGGRFRLTPVYDVLSVYPILGRGPNQLDPRNAQLAMAVHGKNRHRKLHLVRRRHWNETARACGVADGAEPWIKTLIAAVE
PAIQQVTRQLPDDFPSNVSEPIFNGLRAAAARLSSMAPEA

Download         Length: 1323 bp

>T151878 NZ_CP065824:4041526-4041876 [Pseudomonas tolaasii]
ATGGGTGCTCTATTTATCGAACTGCCGGCCTTCGAACGGCATCGCAAGGACTACTTGAGTGACGAGCTTTTTCACGGTTT
TCAACAGGAATTAATGAAAAACCCGGAAGCAGGCGATGTGATTGAAGGAACAAGCGGCCTACGAAAAGTTCGTTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTATTACTGGTGGTCGGGCGGTACGCAATTCTGGTTG
TTCACCCTGTACGGCAAACACGAACAGGACGACCTGACACCCCACCACAAAAAAGCGCTTAAACACATGCTGGACAGGGA
AATCAAAGCGAGAGCACATGATGAAACGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9584.97 Da        Isoelectric Point: 11.8468

>AT151878 WP_005407534.1 NZ_CP049956:c4420875-4420618 [Stenotrophomonas maltophilia]
MDRPLHTVRTAQQLAPLMRAFRRQAGLSQAQLAERLGISRQAVGALERDPASASFERLMRIWAVLGLEVSLQQRSPQENT
SSLEW

Download         Length: 258 bp

>AT151878 NZ_CP065824:4041866-4042183 [Pseudomonas tolaasii]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTTGACGCCCTGGCGGACGAACGCCAAGGCAAAATCACCCTGCG
TACCCACAAGGTTCACCTCAACAAGCTGGAACCGCTCACCGCCGAGGAAGTGGTCGCCGTGCGCCAGCAACTCAACCTCT
CCCGGTCGGTGTTCGCGATGTATCTGCGCACCAACACCCGCACCCTGGAAAACTGGGAGCAAGGCCGGGCCAAGCCCAAT
GCCCAAGCCGTCACCCTGATTCGTCTGGTGGCGCGCTTTCCGGAAACCGTTGCACAATTGGCAGCCCTGGGTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References