Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1983592..1983736 Replicon chromosome
Accession NZ_CP049953
Organism Klebsiella pneumoniae strain 19KM1109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1983628..1983730 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1983592..1983736 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9175_RS09735 1978722..1980782 + 2061 WP_004151449.1 oligopeptidase B -
G9175_RS09740 1980786..1981445 - 660 WP_002911407.1 exodeoxyribonuclease X -
G9175_RS09745 1981524..1981754 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G9175_RS09750 1981867..1982241 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G9175_RS09755 1982245..1983114 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
G9175_RS09760 1983131..1983469 + 339 WP_002911404.1 YebY family protein -
- 1983592..1983736 - 145 - - Antitoxin
- 1983628..1983730 + 103 - - Toxin
G9175_RS09765 1983863..1984222 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
G9175_RS09770 1984221..1984700 + 480 WP_032419797.1 lysis protein -
G9175_RS09775 1985867..1986994 + 1128 WP_064147220.1 hypothetical protein -
G9175_RS09780 1987244..1987672 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
G9175_RS09785 1987682..1987963 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T151862 NZ_CP049953:1983628-1983730 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT151862 NZ_CP049953:c1983736-1983592 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References