Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2184554..2185208 Replicon chromosome
Accession NZ_CP049934
Organism Leucobacter insecticola strain HDW9B

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G7067_RS10090 Protein ID WP_166323948.1
Coordinates 2184554..2184973 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G7067_RS10095 Protein ID WP_166323950.1
Coordinates 2184963..2185208 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7067_RS10075 2182267..2182818 - 552 WP_166323944.1 hypothetical protein -
G7067_RS10080 2182832..2183863 - 1032 WP_166326069.1 nitronate monooxygenase -
G7067_RS10085 2183933..2184502 + 570 WP_166323946.1 dihydrofolate reductase family protein -
G7067_RS10090 2184554..2184973 - 420 WP_166323948.1 PIN domain nuclease Toxin
G7067_RS10095 2184963..2185208 - 246 WP_166323950.1 hypothetical protein Antitoxin
G7067_RS10100 2185386..2185523 + 138 Protein_1979 DivIVA domain-containing protein -
G7067_RS10105 2185680..2186234 + 555 WP_166326072.1 GNAT family N-acetyltransferase -
G7067_RS10110 2186250..2186963 + 714 WP_166323952.1 AAA family ATPase -
G7067_RS10115 2187060..2187566 + 507 WP_166323954.1 GNAT family N-acetyltransferase -
G7067_RS10120 2187611..2188006 - 396 WP_166323956.1 type II toxin-antitoxin system VapC family toxin -
G7067_RS10125 2188368..2189960 - 1593 WP_166323958.1 isocitrate lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15431.74 Da        Isoelectric Point: 6.8709

>T151778 WP_166323948.1 NZ_CP049934:c2184973-2184554 [Leucobacter insecticola]
MLLDINVLLALTWDQHVHHRAAHERFAALDYWSTCPATESGLLRLLLTEAVVGRKVSGAEALSQLAAIRRVPGWRFVPDE
QSLAEPVIDMRVLVGRNQVTDLQLVNLAAKNGQQLATFDAALRGSLVPSEQRWVQVWSA

Download         Length: 420 bp

>T151778 NZ_CP065713:c1459920-1459645 [Sphingomonas paucimobilis]
ATGGCTCAAATAAGCTGGTCGGTTCAGGCCTCGCTCCAACTCGCCGCGATCGTCGATTATATAGAGCAGTTCGATCCCGA
CGCCGCCCGGCGCTTGGGTGACAGGCTGATCGACGTCGCCGAATCCTTGCGGCAATTCCCGGATCGCGGCAGGCCCATTT
CCCATGGCCGCCGCGAGATGGTGACGGTTCGCCCCTATGTCCTGCGCTATGAGCATGACGGCGAGACCGTCCTGATCCTC
GGCATTCGCCACGCCGCCCAACTTTCCGACGATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8438.48 Da        Isoelectric Point: 5.0022

>AT151778 WP_166323950.1 NZ_CP049934:c2185208-2184963 [Leucobacter insecticola]
MRTTLDIDPAVLSVARAKARAEQISIGRAVSELALAGIQRPSPASLAASGFPVLSGAPGHPVTDELVAEYRDDEARRNDA
A

Download         Length: 246 bp

>AT151778 NZ_CP065713:c1460069-1459908 [Sphingomonas paucimobilis]
ATTTTCGAGCAGCGTGACGAGGCGGCGGAACTGGCCGCCGACGAACGCGCACGGGCCGATTTCAAGGCGGGCCGTTTCGT
AAGCCATGAGAAGATGGCCGAATGGCTGAAGACCTGGGGCACCCCCGATCGCAAGCCCCTGCCCCCCGAATGGCTCAAAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References