Detailed information of TA system TA151774

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 158013..158533
• Replicon: chromosome
• Accession: NZ_CP049934
• Organism: Leucobacter insecticola strain HDW9B

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: G7067_RS00740
• Protein ID: WP_166321318.1
• Coordinates: 158013..158303 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: G7067_RS00745
• Protein ID: WP_166321320.1
• Coordinates: 158300..158533 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G7067_RS00720	153202..154125	-	924	WP_166321311.1	hypothetical protein	-
G7067_RS00725	154227..155090	-	864	WP_166321313.1	hypothetical protein	-
G7067_RS00730	155514..156566	-	1053	WP_166321315.1	aspartate-semialdehyde dehydrogenase	-
G7067_RS00735	156579..157855	-	1277	Protein_143	aspartate kinase	-
G7067_RS00740	158013..158303	-	291	WP_166321318.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G7067_RS00745	158300..158533	-	234	WP_166321320.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
G7067_RS00750	158697..159293	-	597	WP_166321322.1	recombination mediator RecR	-
G7067_RS00755	159297..161909	-	2613	WP_166321324.1	DNA polymerase III subunit gamma and tau	-
G7067_RS00760	162054..163241	-	1188	WP_166321325.1	acetate kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (1-76)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11418.86 Da
• Isoelectric Point: 6.7173

>T151774 WP_166321318.1 NZ_CP049934:c158303-158013 [Leucobacter insecticola]
VSGYRLTPAAQRDLSSIWDYTFEIWNVQQAETYFLDIKEAIERVARDPDRGRSCDDIREGYRRYAVGSHLIFYVLQGDRI
DVMRILHQRMDPTRHV

Nucleotide

• Length: 291 bp

>T151774 NZ_CP065711:c786421-786215 [Staphylococcus carnosus]
ATGCAAAATAGTGTAATTAAAATTGATGGAATGGAAACTGAAGAAGAACAGCATAAATTGCATCAACATCTTATAGAAAT
GACAGGTGTATCTGCAGTGCAAGTGGATATGGATTCAAATGAAGTCAGAATCAGTTATGAAACACCTGTAAATCTCAATA
ATCTTGAAAAAGAAATCTATGATGCAGGTTATCAAATATTAAATTAG

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8340.32 Da
• Isoelectric Point: 4.5338

>AT151774 WP_166321320.1 NZ_CP049934:c158533-158300 [Leucobacter insecticola]
MATNTSISLDEHFSSFLAREVSTGRYRSASEVVRAGLRLLEDQENQMAALRAALVAGEMSGEAEPFDFDAFVAAKKA

Nucleotide

• Length: 234 bp

>AT151774 NZ_CP065711:c786726-786433 [Staphylococcus carnosus]
ATGACCGAAAATGATAAAGCGCACCATTCAGAACAAATCAAATCCAACTTGAAAGCACGACTCAATCGAATTGAAGGACA
AGTCAGAGCAATTAACCGAATGATTGAAGAGGATGTATATTGTGATGATGTACTCACACAAATCCGTGCAACACGTTCAG
CTTTGAACAGTGTGGCAGTACGATTGCTTGATCATCACATGAAAGGTTGTATCATGCATAAAGTTGAGGATGGTCACGCT
GAAGAAGCGATGGAAGAATTGCTTGTTACCGTTCAAAAATTGATTAAAGATTAA