Detailed information of TA system TA151768

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-TIGR02293
• Location: 959654..960552
• Replicon: chromosome
• Accession: NZ_CP049919
• Organism: Kinneretia sp. DAIF2

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: G8A07_RS04485
• Protein ID: WP_195795900.1
• Coordinates: 960076..960552 (+)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: G8A07_RS04480
• Protein ID: WP_195795899.1
• Coordinates: 959654..960079 (+)
• Length: 142 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G8A07_RS04455	954903..955220	-	318	WP_195795895.1	hypothetical protein	-
G8A07_RS04460	955223..956017	-	795	WP_195795896.1	hypothetical protein	-
G8A07_RS04465	956327..957387	+	1061	Protein_884	IS3 family transposase	-
G8A07_RS04470	957746..958357	+	612	WP_195795897.1	hypothetical protein	-
G8A07_RS04475	958832..959344	-	513	WP_195795898.1	hypothetical protein	-
G8A07_RS04480	959654..960079	+	426	WP_195795899.1	DUF2384 domain-containing protein	Antitoxin
G8A07_RS04485	960076..960552	+	477	WP_195795900.1	RES family NAD+ phosphorylase	Toxin
G8A07_RS04490	960620..960856	+	237	WP_195795901.1	hypothetical protein	-
G8A07_RS04495	960851..962737	-	1887	WP_195795902.1	DUF4209 domain-containing protein	-
G8A07_RS04500	963379..964017	+	639	WP_195795903.1	hypothetical protein	-
G8A07_RS04505	964349..965128	-	780	WP_195795904.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	928067..964017	35950
	-	flank	IS/Tn	-	-	956327..956587	260

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-153)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (93-138)

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17199.70 Da
• Isoelectric Point: 4.9044

>T151768 WP_195795900.1 NZ_CP049919:960076-960552 [Kinneretia sp. DAIF2]
VSVALWRIATDTRDYEAHDLSGKGAEVSGGRWNRPGRPVVYTASSIALACLEAVVHLNMAGLPLNRFLVRIDVPDALWAA
RQVLTAQELPLGWSAVPEGKVSLDVGDQWLQGDADALLLVPSVIVPEEFDVLINPQHADAAGIMAQKVRPWRYDGRLV

Nucleotide

• Length: 477 bp

>T151768 NZ_CP065706:870021-870209 [Streptococcus oralis]
ATGCCACTTACAGGTAAAGAAATGGTGAAACTAGCTCTTGAGAATGGATGGGTTGAAGTTCGTCAAAGGGGAAGTCATCA
TCATTTTAAGAAAGAGGGTTTTTCTTATCTTGTCACGATTCCAGTTCATGGAAATGAAGATTTAGGAAGAGGTTTGGAAA
GAAAGATTCTCAAAGATTTAGGATTGTAA

Antitoxin

Protein

• Length: 142 a.a.
• Molecular weight: 15577.94 Da
• Isoelectric Point: 9.9146

>AT151768 WP_195795899.1 NZ_CP049919:959654-960079 [Kinneretia sp. DAIF2]
MNFLTVFQADAFERVRWVKQGIPASAVEHIAKRMAMPKERLVLTLGLARATVDRKARENKSLSTDESSRVLGMARLVGQV
EFIVEESGNPIGFNAAEWVARWLEQPLPALGGRRPAEFMDTPDGQALVSNLVARMYSGAHA

Nucleotide

• Length: 426 bp

>AT151768 NZ_CP065706:870250-870627 [Streptococcus oralis]
ATGTTAAAAACGTATCCAGCTATTTTTCATAAAGAAGGAACAGGATATTGGGTAGAATTTCCAGAATTTGGTGGTGGTAC
AGAAGGAAAAAATATCGAGGAAGCGATGAAAAATGCTCGTGAAATGCTTGAAAATGTTTTAGCTTCTTATATCGATGAAG
GGATGGCGCTGCCTACACCAAGTGATATTTTAAAGATTGAAGTTTCAGATGGTTTTGTATCAATGATTCAAGTCGATCCT
GCGCCCTTTGTGAGAAGTAATAAGGCGATTAGGAAGAATGTGACCGTTCCTGAATGGCTAGTTCGTCTTGCTGATCGAGA
AAAGATTAACTATTCAGAAGTTTTGGCGCAAGCGCTAGAGAAGAAGTTGCAAGTTTAA