Detailed information of TA system TA151753

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 3641241..3642739
• Replicon: chromosome
• Accession: NZ_CP049910
• Organism: Diaphorobacter sp. HDW4A

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: G7047_RS16600
• Protein ID: WP_166307743.1
• Coordinates: 3641837..3642739 (+)
• Length: 301 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: G7047_RS16595
• Protein ID: WP_205904645.1
• Coordinates: 3641241..3641840 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G7047_RS16580	3636460..3638037	+	1578	WP_166307735.1	AMP-binding protein	-
G7047_RS16585	3638199..3639503	+	1305	WP_166307737.1	MFS transporter	-
G7047_RS16590	3639819..3641168	+	1350	WP_166307739.1	site-specific integrase	-
G7047_RS16595	3641241..3641840	+	600	WP_205904645.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
G7047_RS16600	3641837..3642739	+	903	WP_166307743.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
G7047_RS16605	3642767..3643540	-	774	WP_166312108.1	site-specific integrase	-
G7047_RS16610	3643870..3644220	-	351	WP_166307745.1	hypothetical protein	-
G7047_RS16615	3644223..3644585	-	363	WP_166307747.1	hypothetical protein	-
G7047_RS16620	3644810..3645067	-	258	WP_166307749.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
G7047_RS16625	3645077..3646584	-	1508	Protein_3273	IS66 family transposase	-
G7047_RS16630	3646656..3646988	-	333	WP_166301587.1	IS66 family insertion sequence element accessory protein TnpB	-
G7047_RS30955	3646985..3647395	-	411	WP_205904646.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-257)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (7-52)

Sequences

Toxin

Protein

• Length: 301 a.a.
• Molecular weight: 32765.57 Da
• Isoelectric Point: 6.4969

>T151753 WP_166307743.1 NZ_CP049910:3641837-3642739 [Diaphorobacter sp. HDW4A]
MIGNLSASILARLLTLAKQRGDDYNLLLNRFGMERLLARVSTSPHADRFLLKGALLFALWYDTPHRPTRDADLLGFGPDD
EANLIATFRDIAAMDLGDGIVFDPDSVKADAIREDNTYGGTRITLVARIGSARCALQIDVGFGDAVTPGPQTVAYPTLLG
DFPAPTLRVYPVYTVIAEKYQAMVMLGQANSRMKDFFDLAVIARRTELDGATLAAAIAATFARRQTALPTERPLALTKQF
SADTAKLRQWQAFLNKNRIEAASLGDTVALLDDLLWPPTEVAAAGSQAKATWRPDALRWV

Nucleotide

• Length: 903 bp

>T151753 NZ_CP065699:c2181340-2181026 [Serratia plymuthica]
ATGCAATTTACGGTATACGCGAATACAGGGAAAAGCGCAGTCTATCCTCTGCTGCTTGATGTGACGAGCGATATCATTGG
GCAATTAAATCGCCGAGTTGTGATCCCGTTATTACCCATTGAAAAGTATCCGGCCAGTACTCGCCCGGAACGCTTGAACC
CTTTGGTCAGGCTGGTGGATGACAACGAGTACGCCGTTATGACCCATGAGATGGCAAGTATTCCCGTTCGTATCCTGGGC
GCTGAATTTTGCGATGCTTCCCAATACCGAACCAAGGTGAAAGCCGCAATAGATTTTCTTTTCGACGGTATCTGA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22614.08 Da
• Isoelectric Point: 9.4662

>AT151753 WP_205904645.1 NZ_CP049910:3641241-3641840 [Diaphorobacter sp. HDW4A]
MHQSDHILELARHRRVLRAADVREHGWSPQLLLRLHQAGKLQRFARGLYGLPDAEVTEHQTLIEVCQRVPKAVLCLLSAL
QFHEIGTQMSHEVWIALPEGTQTPALSYPTLRITRLRGTAYSDGIETVTDHGASIRVYSAAKTVTDCFKFRNKIGLDVAL
EALKDAWRSRKVTMAELNHFAKINRVERVMQPYLEAVTQ

Nucleotide

• Length: 600 bp

>AT151753 NZ_CP065699:c2181579-2181343 [Serratia plymuthica]
ATGCCAGTAAAACAACGAACGACCCAAAGCGTTACCATGGCGGTGGAACGCAGTTTACTGAGCCGTGCACGTGAGGCGGG
CATTAACCTCAGTGCTACGCTGAATGCTGCTTTGGATGCAGAATTGCGTCAGCATGAGATGAGAAAATGGAAGGAAGAAA
ACCGAGAAGCGATCGATGCTTTAAATCGTTTTCATGATGAACATGGCTGTTTCAGTGACGAATACAGGACGTTTTAG