Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-StbC
Location 1994955..1995652 Replicon chromosome
Accession NZ_CP049863
Organism Leucobacter viscericola strain HDW9C

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G7068_RS08860 Protein ID WP_166291244.1
Coordinates 1995224..1995652 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G7068_RS08855 Protein ID WP_166291242.1
Coordinates 1994955..1995227 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7068_RS08835 1990611..1991837 + 1227 WP_166291235.1 sensor histidine kinase -
G7068_RS08840 1991834..1992517 + 684 WP_166291237.1 response regulator transcription factor -
G7068_RS08845 1992606..1993334 + 729 WP_205881262.1 ATP-binding cassette domain-containing protein -
G7068_RS08850 1993331..1994632 + 1302 WP_166291240.1 ABC transporter permease -
G7068_RS08855 1994955..1995227 + 273 WP_166291242.1 Arc family DNA-binding protein Antitoxin
G7068_RS08860 1995224..1995652 + 429 WP_166291244.1 PIN domain-containing protein Toxin
G7068_RS08865 1995658..1998573 - 2916 WP_166293086.1 FAD-binding oxidoreductase -
G7068_RS08870 1998829..1999749 - 921 WP_166291246.1 alpha/beta hydrolase -
G7068_RS08875 1999807..2000631 - 825 WP_166291248.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)

Antitoxin

Arc-like DNA binding domain

(9-38)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15537.78 Da        Isoelectric Point: 6.3224

>T151739 WP_166291244.1 NZ_CP049863:1995224-1995652 [Leucobacter viscericola]
MSRYLLDTNVLIALLDPAQQFHAAANRWFYGGAMRDWLSCPITENGTVRIISLPKYPGARTPGMVLESLGTLLTVGNHEH
IADDVSLLSPDIDPSRLETSAQVTDTYLALLAHKHGAQLATFDRRISTAALRVPGEVFQVPV

Download         Length: 429 bp

>T151739 NZ_CP065693:c1940181-1939852 [Enterobacter asburiae]
ATGAAAACTCTACCTGCTACAATTTCGCGGGCGGCGAAGCCCTGTCTGTCGCCCGTTGCAGTCTGGCAAATGTTACTTAC
TCGTCTGCTTGAGCAGCACTATGGCCTAATGCTAAGCGACACACCTTTTAGCGATGAAACCGTTATAAAGGAGCATATCG
ATGCCGGTATCACTCTGGCTAATGCTGTTAATTTTCTGGTGGAAAAATACGAACTGGTTCGTATCGACCGAAAGGGATTT
TCGTGGCAAGAACAAACCCCGTATCTTTCCGTAGTGGATATTCTGCGAGCAAGGCGCTCTAGCGGCTTGCTAAAAACTAA
CGTGAAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10088.35 Da        Isoelectric Point: 4.2187

>AT151739 WP_166291242.1 NZ_CP049863:1994955-1995227 [Leucobacter viscericola]
MAQLLIRQLPDEVKEGLRERARASGRSMEAEARAILTDFIFPTNEVSLEYDGPQDATTLFERYGVKILPSRPEGGVVSFE
ETQALIDEFA

Download         Length: 273 bp

>AT151739 NZ_CP065693:c1940519-1940202 [Enterobacter asburiae]
ATGAGCAACATTACATGGGGCCTGCAGCGGGATACCACGCCGCGTCTGGGAGCCCGTCTGGTACAGGAGGGGAACCAACT
GCATTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGATGCCGAATGTTTTAAGCTGGATGTGGCATTTCCGC
ATTTTATCAGTCAGATGGAATCGATGCTGACCACTGGTGAAATGAATCCCCGCCATGCCCGCTGTGTCACCCTGTACCAC
AACGGTTTCACCTGCGAAGCCGATACCCTTGGTAGTTGCGGCTACGTATACATCGCCATTTATCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References