Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 3241932..3242605 | Replicon | chromosome |
| Accession | NZ_CP049862 | ||
| Organism | Sanguibacter sp. HDW7 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | G7063_RS14615 | Protein ID | WP_166415037.1 |
| Coordinates | 3241932..3242369 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | G7063_RS14620 | Protein ID | WP_166415038.1 |
| Coordinates | 3242366..3242605 (-) | Length | 80 a.a. |
Genomic Context
Location: 3237543..3238013 (471 bp)
Type: Others
Protein ID: WP_206188286.1
Type: Others
Protein ID: WP_206188286.1
Location: 3239559..3240896 (1338 bp)
Type: Others
Protein ID: WP_166415034.1
Type: Others
Protein ID: WP_166415034.1
Location: 3240893..3241378 (486 bp)
Type: Others
Protein ID: WP_166415035.1
Type: Others
Protein ID: WP_166415035.1
Location: 3241378..3241854 (477 bp)
Type: Others
Protein ID: WP_166415036.1
Type: Others
Protein ID: WP_166415036.1
Location: 3238072..3238344 (273 bp)
Type: Others
Protein ID: WP_206188170.1
Type: Others
Protein ID: WP_206188170.1
Location: 3238349..3239395 (1047 bp)
Type: Others
Protein ID: WP_166415407.1
Type: Others
Protein ID: WP_166415407.1
Location: 3241932..3242369 (438 bp)
Type: Toxin
Protein ID: WP_166415037.1
Type: Toxin
Protein ID: WP_166415037.1
Location: 3242366..3242605 (240 bp)
Type: Antitoxin
Protein ID: WP_166415038.1
Type: Antitoxin
Protein ID: WP_166415038.1
Location: 3242704..3243951 (1248 bp)
Type: Others
Protein ID: WP_166415039.1
Type: Others
Protein ID: WP_166415039.1
Location: 3243965..3244711 (747 bp)
Type: Others
Protein ID: WP_166415040.1
Type: Others
Protein ID: WP_166415040.1
Location: 3244708..3245310 (603 bp)
Type: Others
Protein ID: WP_166415408.1
Type: Others
Protein ID: WP_166415408.1
Location: 3245493..3247295 (1803 bp)
Type: Others
Protein ID: WP_166415041.1
Type: Others
Protein ID: WP_166415041.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G7063_RS14585 | 3237543..3238013 | + | 471 | WP_206188286.1 | molybdenum cofactor biosynthesis protein MoaE | - |
| G7063_RS14590 | 3238072..3238344 | - | 273 | WP_206188170.1 | MoaD/ThiS family protein | - |
| G7063_RS14595 | 3238349..3239395 | - | 1047 | WP_166415407.1 | GTP 3',8-cyclase MoaA | - |
| G7063_RS14600 | 3239559..3240896 | + | 1338 | WP_166415034.1 | molybdopterin molybdotransferase MoeA | - |
| G7063_RS14605 | 3240893..3241378 | + | 486 | WP_166415035.1 | cyclic pyranopterin monophosphate synthase MoaC | - |
| G7063_RS14610 | 3241378..3241854 | + | 477 | WP_166415036.1 | MogA/MoaB family molybdenum cofactor biosynthesis protein | - |
| G7063_RS14615 | 3241932..3242369 | - | 438 | WP_166415037.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| G7063_RS14620 | 3242366..3242605 | - | 240 | WP_166415038.1 | plasmid stability protein | Antitoxin |
| G7063_RS14625 | 3242704..3243951 | - | 1248 | WP_166415039.1 | ThiF family adenylyltransferase | - |
| G7063_RS14630 | 3243965..3244711 | - | 747 | WP_166415040.1 | respiratory nitrate reductase subunit gamma | - |
| G7063_RS14635 | 3244708..3245310 | - | 603 | WP_166415408.1 | nitrate reductase molybdenum cofactor assembly chaperone | - |
| G7063_RS14640 | 3245493..3247295 | - | 1803 | WP_166415041.1 | nitrate reductase subunit beta | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15427.84 Da Isoelectric Point: 4.6533
>T151737 WP_166415037.1 NZ_CP049862:c3242369-3241932 [Sanguibacter sp. HDW7]
VIVLDTNVLSEAVRPTPAPQVIEWIDAQHVETLYVSVLTVAELRLGLAVLPDGARRSMLTQRLEDEVFPLFEGRVLPVDG
AVALEFARLQAAARSGGMTMPVIDALIAATCSAHRFTLATRNVADFAASGVPLIDPWRAPGASGV
VIVLDTNVLSEAVRPTPAPQVIEWIDAQHVETLYVSVLTVAELRLGLAVLPDGARRSMLTQRLEDEVFPLFEGRVLPVDG
AVALEFARLQAAARSGGMTMPVIDALIAATCSAHRFTLATRNVADFAASGVPLIDPWRAPGASGV
Download Length: 438 bp
>T151737 NZ_CP065693:946191-946562 [Enterobacter asburiae]
ATGGAGCACATGGCAGTGTTTGATACCAATATTCTCATCGATCTTTTTAATAATCGTGTTGAGGCGGCGGATGCCATTGA
TCGCACGGCGTCGCATAGAGCCATTAGCCTGATCACGTGGATGGAGGTCATGGTGGGTGCGCGCAAGCACGGACATGAAG
CAAAAACGGCGGCTGTGATGGGGGCTTTTGAGATTATTGATATTTCTCGGGATATCGCAGAAAGAAGCGTTTTACTTCGC
GAGAAACATGGGATGAAACTGCCTGATGCCATTATTCTGGCTACTGCTCAGAGCAGAAGTTGCCCGTTAATCTCACGCAA
TACGAAAGACTTTTCGGGCATTACTGGAGTCGTTTCACCTTACCAGCTGTAG
ATGGAGCACATGGCAGTGTTTGATACCAATATTCTCATCGATCTTTTTAATAATCGTGTTGAGGCGGCGGATGCCATTGA
TCGCACGGCGTCGCATAGAGCCATTAGCCTGATCACGTGGATGGAGGTCATGGTGGGTGCGCGCAAGCACGGACATGAAG
CAAAAACGGCGGCTGTGATGGGGGCTTTTGAGATTATTGATATTTCTCGGGATATCGCAGAAAGAAGCGTTTTACTTCGC
GAGAAACATGGGATGAAACTGCCTGATGCCATTATTCTGGCTACTGCTCAGAGCAGAAGTTGCCCGTTAATCTCACGCAA
TACGAAAGACTTTTCGGGCATTACTGGAGTCGTTTCACCTTACCAGCTGTAG
Antitoxin
Download Length: 80 a.a. Molecular weight: 8315.44 Da Isoelectric Point: 6.2180
>AT151737 WP_166415038.1 NZ_CP049862:c3242605-3242366 [Sanguibacter sp. HDW7]
MAAMTVRGISDETHRALKLRAAAHGRSAEAEVRAILDAAVADEGRVRLGSLLADIGHAAGGVELEIVRDRTPYEPVNLG
MAAMTVRGISDETHRALKLRAAAHGRSAEAEVRAILDAAVADEGRVRLGSLLADIGHAAGGVELEIVRDRTPYEPVNLG
Download Length: 240 bp
>AT151737 NZ_CP065693:945946-946188 [Enterobacter asburiae]
ATGAGTCTTTCCGCGGATCTTGATATGGGCAGAATTCTGATCGATTTGTCTGATGACGTAATTCAACGACTGGATAATCT
GAAGCAGCTGCGTAACCAACCTCGTGCCGAATTACTGCGTGAAGCAATTGAGCAATATCTCGACCAGCAGAGTTCATCGG
TTATCCGCGATGCGCTTGGCCTGTGGGGAAACCAGCAGGAAGATGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA
ATGAGTCTTTCCGCGGATCTTGATATGGGCAGAATTCTGATCGATTTGTCTGATGACGTAATTCAACGACTGGATAATCT
GAAGCAGCTGCGTAACCAACCTCGTGCCGAATTACTGCGTGAAGCAATTGAGCAATATCTCGACCAGCAGAGTTCATCGG
TTATCCGCGATGCGCTTGGCCTGTGGGGAAACCAGCAGGAAGATGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA