Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 459522..460017 Replicon chromosome
Accession NZ_CP049859
Organism Erysipelothrix sp. HDW6A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G7059_RS02445 Protein ID WP_205700224.1
Coordinates 459522..459797 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G7059_RS02450 Protein ID WP_166080510.1
Coordinates 459790..460017 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7059_RS02425 454736..455439 + 704 Protein_469 SIS domain-containing protein -
G7059_RS02430 455497..456276 - 780 WP_166080507.1 MurR/RpiR family transcriptional regulator -
G7059_RS02435 456290..457594 - 1305 WP_166080508.1 PTS sugar transporter subunit IIC -
G7059_RS02440 457831..459192 - 1362 WP_166080509.1 5'-nucleotidase C-terminal domain-containing protein -
G7059_RS02445 459522..459797 - 276 WP_205700224.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
G7059_RS02450 459790..460017 - 228 WP_166080510.1 DUF1778 domain-containing protein Antitoxin
G7059_RS02460 460478..460951 - 474 WP_166080511.1 hypothetical protein -
G7059_RS02465 460951..461730 - 780 WP_166080512.1 hypothetical protein -
G7059_RS02470 461740..462153 - 414 WP_166080513.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
G7059_RS02475 462309..463208 + 900 WP_166080515.1 nucleotidyltransferase -
G7059_RS02480 463243..464088 - 846 WP_166080516.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-89)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10713.64 Da        Isoelectric Point: 10.5413

>T151736 WP_205700224.1 NZ_CP049859:c459797-459522 [Erysipelothrix sp. HDW6A]
MSSMYRVVFSKGFEKSINKIDKKQQVILLNKLMLDLDSSVNPRQFGKALVGNLKGLWRYRYGDYRIIVHIQDNELIILAL
EVGHRKDKYKK

Download         Length: 276 bp

>T151736 NZ_CP065693:c837104-836790 [Enterobacter asburiae]
ATGCATTTAATCTCTATGAAAGCTATTTTGGATGCGGTAACCCAGTTTCCGCAGCACAAGGATGAACTCCTTTTTTTGGG
TCGCACCATCGAAAAGAGCCATTGCCCAACACCTGCTGCTCTGAAAAAACTGTTTCCGACGCTGGATAACTTTAAGTATC
TGGATAAGCATTATGTTATTGATATTGCAAACAACAATCTCAGAGTAGTGGCTCTCATATTCTTTGAAAGCCAAAAGTTT
TATGTGCGCCATGTTTTTACTCATAAGGAATATGACCGTTTTACGGAGAAACATCGCACTAAGGGGAAGAAATGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8845.12 Da        Isoelectric Point: 4.5463

>AT151736 WP_166080510.1 NZ_CP049859:c460017-459790 [Erysipelothrix sp. HDW6A]
MSTITIRTTEKEKKLIQEYAKFNGMTISDFIKKSMIEKIEDEYDYQVGERAYKEYLTSGEKPMPIADLLEKIENE

Download         Length: 228 bp

>AT151736 NZ_CP065693:c836793-836374 [Enterobacter asburiae]
ATGATGATCGTCGCTGATGCAATGAAAGCTACGCATGCCCTTGTTGCGGCCGTTCCTTTACTGGGTGAACAGCCGAGCGA
GAAAGATTATGAGGATGCGCTAGAGCTGGTTGAGTATCTTCTTATGAACGAGCCCGATAGCCCCTTGTTGGATATTGTGT
GCGCCAGGATTAGCCGTTACGAAGCCAATCGGCCAGATATTGTCGCATTACGCAAGGAGATGGAGTCCGTTCCCGTCGGT
ATTGCGGTTTTAAGAACCTTGATGGATCAGTACAACCTGACGATATCGGATTTTGAGGATGAAATTGGCAGTAAATCGAT
GGTTTCACGGGTTCTGAATGGTCAGAGACAGCTTACTCTGAACCATATTAAAAAGCTGGCGGCGAGGTTTGGGGTATCAC
CTGCGCTGTTTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References