151637

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 4328782..4329455 Replicon chromosome
Accession NZ_CP049836
Organism Gordonia terrae strain RL-JC02

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G8C36_RS19245 Protein ID WP_137810536.1
Coordinates 4328782..4329186 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G8C36_RS19250 Protein ID WP_137810537.1
Coordinates 4329183..4329455 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G8C36_RS19235 4326108..4327037 + 930 WP_137810535.1 DUF2236 domain-containing protein -
G8C36_RS19240 4327104..4328780 + 1677 WP_065631752.1 DEAD/DEAH box helicase -
G8C36_RS19245 4328782..4329186 - 405 WP_137810536.1 type II toxin-antitoxin system VapC family toxin Toxin
G8C36_RS19250 4329183..4329455 - 273 WP_137810537.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G8C36_RS19255 4329588..4331267 - 1680 WP_137810538.1 serine/threonine protein kinase -
G8C36_RS19260 4331365..4332531 + 1167 WP_137810539.1 pyridoxal phosphate-dependent aminotransferase -
G8C36_RS19265 4333048..4334031 - 984 WP_165630431.1 LLM class F420-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-46)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14167.42 Da        Isoelectric Point: 4.6533

>T151637 WP_137810536.1 NZ_CP049836:c4329186-4328782 [Gordonia terrae]
MIYLDTSAMVKLVVREAETAPLIEWFALRPGVPTVTSALGRVELMRTALRDGSPGLHERARDLLDALDVIPLSAAVIDIA
ESIGPSSLRSLDALHLASATVIRAEMTAFVAYDQRLTAGASALGYPVVAPGAEL

Download         Length: 405 bp

>T151637 NZ_CP065624:c4292301-4292194 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9823.27 Da        Isoelectric Point: 11.0590

>AT151637 WP_137810537.1 NZ_CP049836:c4329455-4329183 [Gordonia terrae]
MRTIGIRELRQHASRYLAQVEAGEELAITNRGRTVARLVPVSAGERSREALIEAGILVPARSAGGITGLHPETLPTRALT
KVLDQVREDR

Download         Length: 273 bp

>AT151637 NZ_CP065624:4292349-4292415 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References