Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 966794..967455 Replicon chromosome
Accession NZ_CP049793
Organism Ralstonia solanacearum strain 204

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E7Z845
Locus tag G7939_RS04760 Protein ID WP_016727753.1
Coordinates 966794..967207 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E7Z6P3
Locus tag G7939_RS04765 Protein ID WP_019717749.1
Coordinates 967204..967455 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7939_RS04730 962112..963359 - 1248 WP_081365215.1 tyrosine-type recombinase/integrase -
G7939_RS04735 963520..963909 + 390 WP_089190402.1 hypothetical protein -
G7939_RS04740 963906..964127 + 222 WP_089190401.1 hypothetical protein -
G7939_RS04745 964102..964746 + 645 WP_089190400.1 hypothetical protein -
G7939_RS04750 964789..965076 - 288 WP_089190399.1 H-NS histone family protein -
G7939_RS04755 965700..966722 + 1023 WP_020425162.1 DNA cytosine methyltransferase -
G7939_RS04760 966794..967207 - 414 WP_016727753.1 type II toxin-antitoxin system VapC family toxin Toxin
G7939_RS04765 967204..967455 - 252 WP_019717749.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G7939_RS04770 967730..968605 - 876 WP_049800423.1 hypothetical protein -
G7939_RS04775 969202..969434 + 233 Protein_944 hypothetical protein -
G7939_RS04780 969588..969803 - 216 WP_071615547.1 hypothetical protein -
G7939_RS25740 970077..970415 + 339 WP_016727784.1 glycine zipper 2TM domain-containing protein -
G7939_RS04790 971090..971806 - 717 WP_049800424.1 Crp/Fnr family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15586.89 Da        Isoelectric Point: 6.2337

>T151604 WP_016727753.1 NZ_CP049793:c967207-966794 [Ralstonia solanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

>T151604 NZ_CP065615:2365829-2366047 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9305.49 Da        Isoelectric Point: 5.0774

>AT151604 WP_019717749.1 NZ_CP049793:c967455-967204 [Ralstonia solanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp

>AT151604 NZ_CP065615:2365429-2365803 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References